Magnitude of visceral leishmaniasis and HIV coinfection and association with social determinants of health in the Northeast region of Brazil: a retrospective, spatiotemporal model (2010–2018)

Erica Santos dos Reis; Caíque Jordan Nunes Ribeiro; Allan Dantas dos Santos; Damião da Conceição Araújo; Márcio Bezerra-Santos; Eliete Rodrigues da Silva; Rogério Silva Santos; Wandklebson Silva Paz; Rosália Elen Santos Ramos; Priscila Lima dos Santos; Michael Wheeler Lipscomb; Karina Conceição Gomes M. de Araújo; Tatiana Rodrigues de Moura

doi:10.1007/s00436-022-07450-6

Magnitude of visceral leishmaniasis and HIV coinfection and association with social determinants of health in the Northeast region of Brazil: a retrospective, spatiotemporal model (2010–2018)

Erica Santos dos Reis, Caíque Jordan Nunes Ribeiro, Allan Dantas dos Santos, Damião da Conceição Araújo, Márcio Bezerra-Santos, Eliete Rodrigues da Silva, Rogério Silva Santos, Wandklebson Silva Paz, Rosália Elen Santos Ramos, Priscila Lima dos Santos, Michael Wheeler Lipscomb, Karina Conceição Gomes M. de Araújo, Tatiana Rodrigues de Moura

Pharmacology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The Northeast region of Brazil (NRB) includes the states with the highest prevalence of visceral leishmaniasis (VL), as well as those with significant increases in HIV cases. This study aims to analyze the spatiotemporal patterns of VL-HIV coinfection and its association with the social determinants of health (SDH) in the NRB. Time trend analysis and Bayesian spatial statistical inferences, Moran’s autocorrelation, and retrospective space–time scanning were performed. Spatial regression modelling was used to build an explanatory model for the occurrence of VL-HIV coinfection within NRB. A total of 1550 cases of VL-HIV coinfection were confirmed. We observed a higher prevalence among males (1232; 83%), individuals aged from 20 to 59 years (850; 54.8%), non-white skin color (1,422; 91.7%), and with low education (550; 35.48%). NRB showed an increasing and significant trend in the detection rate of coinfection (APC, 5.3; 95% CI, 1.4 to 9.4). The states of Maranhão and Piauí comprised the high-risk cluster. The SDH that most correlated with the occurrence of coinfection were poor housing, low income, and low education. VL-HIV is dispersed in the NRB but chiefly affects states with greater social vulnerability. Taken together, these findings reinforce the necessity to implement surveillance strategies that will contribute to the reduction of cases in these populations.

Original language	English (US)
Pages (from-to)	1021-1031
Number of pages	11
Journal	Parasitology Research
Volume	121
Issue number	3
DOIs	https://doi.org/10.1007/s00436-022-07450-6
State	Published - Mar 2022

Bibliographical note

Funding Information:
This work was supported by the Fundação de Apoio a Pesquisa e à Inovação Tecnológica do Estado de Sergipe (FAPITC/SE) (EDITAL FAPITEC/SE/FUNTEC/CAPES N° 07/2018). The funding helped in the conception of the study and collection and analysis of the data.

Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Keywords

Epidemiology
Neglected diseases
Spatial analysis
Spatial regression

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1007/s00436-022-07450-6

Find It

Find It at U of M Libraries

Cite this

dos Reis, E. S., Ribeiro, C. J. N., dos Santos, A. D., da Conceição Araújo, D., Bezerra-Santos, M., da Silva, E. R., Santos, R. S., Paz, W. S., Ramos, R. E. S., dos Santos, P. L., Lipscomb, M. W., de Araújo, K. C. G. M., & de Moura, T. R. (2022). Magnitude of visceral leishmaniasis and HIV coinfection and association with social determinants of health in the Northeast region of Brazil: a retrospective, spatiotemporal model (2010–2018). Parasitology Research, 121(3), 1021-1031. https://doi.org/10.1007/s00436-022-07450-6

Magnitude of visceral leishmaniasis and HIV coinfection and association with social determinants of health in the Northeast region of Brazil: a retrospective, spatiotemporal model (2010–2018). / dos Reis, Erica Santos; Ribeiro, Caíque Jordan Nunes; dos Santos, Allan Dantas et al.
In: Parasitology Research, Vol. 121, No. 3, 03.2022, p. 1021-1031.

Research output: Contribution to journal › Article › peer-review

dos Reis, ES, Ribeiro, CJN, dos Santos, AD, da Conceição Araújo, D, Bezerra-Santos, M, da Silva, ER, Santos, RS, Paz, WS, Ramos, RES, dos Santos, PL, Lipscomb, MW, de Araújo, KCGM & de Moura, TR 2022, 'Magnitude of visceral leishmaniasis and HIV coinfection and association with social determinants of health in the Northeast region of Brazil: a retrospective, spatiotemporal model (2010–2018)', Parasitology Research, vol. 121, no. 3, pp. 1021-1031. https://doi.org/10.1007/s00436-022-07450-6

dos Reis ES, Ribeiro CJN, dos Santos AD, da Conceição Araújo D, Bezerra-Santos M, da Silva ER et al. Magnitude of visceral leishmaniasis and HIV coinfection and association with social determinants of health in the Northeast region of Brazil: a retrospective, spatiotemporal model (2010–2018). Parasitology Research. 2022 Mar;121(3):1021-1031. doi: 10.1007/s00436-022-07450-6

@article{00d883e1e33445e0b6724ec898970ad7,

title = "Magnitude of visceral leishmaniasis and HIV coinfection and association with social determinants of health in the Northeast region of Brazil: a retrospective, spatiotemporal model (2010–2018)",

abstract = "The Northeast region of Brazil (NRB) includes the states with the highest prevalence of visceral leishmaniasis (VL), as well as those with significant increases in HIV cases. This study aims to analyze the spatiotemporal patterns of VL-HIV coinfection and its association with the social determinants of health (SDH) in the NRB. Time trend analysis and Bayesian spatial statistical inferences, Moran{\textquoteright}s autocorrelation, and retrospective space–time scanning were performed. Spatial regression modelling was used to build an explanatory model for the occurrence of VL-HIV coinfection within NRB. A total of 1550 cases of VL-HIV coinfection were confirmed. We observed a higher prevalence among males (1232; 83%), individuals aged from 20 to 59 years (850; 54.8%), non-white skin color (1,422; 91.7%), and with low education (550; 35.48%). NRB showed an increasing and significant trend in the detection rate of coinfection (APC, 5.3; 95% CI, 1.4 to 9.4). The states of Maranh{\~a}o and Piau{\'i} comprised the high-risk cluster. The SDH that most correlated with the occurrence of coinfection were poor housing, low income, and low education. VL-HIV is dispersed in the NRB but chiefly affects states with greater social vulnerability. Taken together, these findings reinforce the necessity to implement surveillance strategies that will contribute to the reduction of cases in these populations.",

keywords = "Epidemiology, Neglected diseases, Spatial analysis, Spatial regression",

author = "{dos Reis}, {Erica Santos} and Ribeiro, {Ca{\'i}que Jordan Nunes} and {dos Santos}, {Allan Dantas} and {da Concei{\c c}{\~a}o Ara{\'u}jo}, Dami{\~a}o and M{\'a}rcio Bezerra-Santos and {da Silva}, {Eliete Rodrigues} and Santos, {Rog{\'e}rio Silva} and Paz, {Wandklebson Silva} and Ramos, {Ros{\'a}lia Elen Santos} and {dos Santos}, {Priscila Lima} and Lipscomb, {Michael Wheeler} and {de Ara{\'u}jo}, {Karina Concei{\c c}{\~a}o Gomes M.} and {de Moura}, {Tatiana Rodrigues}",

note = "Funding Information: This work was supported by the Funda{\c c}{\~a}o de Apoio a Pesquisa e {\`a} Inova{\c c}{\~a}o Tecnol{\'o}gica do Estado de Sergipe (FAPITC/SE) (EDITAL FAPITEC/SE/FUNTEC/CAPES N° 07/2018). The funding helped in the conception of the study and collection and analysis of the data. Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",

year = "2022",

month = mar,

doi = "10.1007/s00436-022-07450-6",

language = "English (US)",

volume = "121",

pages = "1021--1031",

journal = "Parasitology Research",

issn = "0932-0113",

publisher = "Springer Verlag",

number = "3",

}

TY - JOUR

T1 - Magnitude of visceral leishmaniasis and HIV coinfection and association with social determinants of health in the Northeast region of Brazil

T2 - a retrospective, spatiotemporal model (2010–2018)

AU - dos Reis, Erica Santos

AU - Ribeiro, Caíque Jordan Nunes

AU - dos Santos, Allan Dantas

AU - da Conceição Araújo, Damião

AU - Bezerra-Santos, Márcio

AU - da Silva, Eliete Rodrigues

AU - Santos, Rogério Silva

AU - Paz, Wandklebson Silva

AU - Ramos, Rosália Elen Santos

AU - dos Santos, Priscila Lima

AU - Lipscomb, Michael Wheeler

AU - de Araújo, Karina Conceição Gomes M.

AU - de Moura, Tatiana Rodrigues

N1 - Funding Information: This work was supported by the Fundação de Apoio a Pesquisa e à Inovação Tecnológica do Estado de Sergipe (FAPITC/SE) (EDITAL FAPITEC/SE/FUNTEC/CAPES N° 07/2018). The funding helped in the conception of the study and collection and analysis of the data. Publisher Copyright: © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

PY - 2022/3

Y1 - 2022/3

N2 - The Northeast region of Brazil (NRB) includes the states with the highest prevalence of visceral leishmaniasis (VL), as well as those with significant increases in HIV cases. This study aims to analyze the spatiotemporal patterns of VL-HIV coinfection and its association with the social determinants of health (SDH) in the NRB. Time trend analysis and Bayesian spatial statistical inferences, Moran’s autocorrelation, and retrospective space–time scanning were performed. Spatial regression modelling was used to build an explanatory model for the occurrence of VL-HIV coinfection within NRB. A total of 1550 cases of VL-HIV coinfection were confirmed. We observed a higher prevalence among males (1232; 83%), individuals aged from 20 to 59 years (850; 54.8%), non-white skin color (1,422; 91.7%), and with low education (550; 35.48%). NRB showed an increasing and significant trend in the detection rate of coinfection (APC, 5.3; 95% CI, 1.4 to 9.4). The states of Maranhão and Piauí comprised the high-risk cluster. The SDH that most correlated with the occurrence of coinfection were poor housing, low income, and low education. VL-HIV is dispersed in the NRB but chiefly affects states with greater social vulnerability. Taken together, these findings reinforce the necessity to implement surveillance strategies that will contribute to the reduction of cases in these populations.

AB - The Northeast region of Brazil (NRB) includes the states with the highest prevalence of visceral leishmaniasis (VL), as well as those with significant increases in HIV cases. This study aims to analyze the spatiotemporal patterns of VL-HIV coinfection and its association with the social determinants of health (SDH) in the NRB. Time trend analysis and Bayesian spatial statistical inferences, Moran’s autocorrelation, and retrospective space–time scanning were performed. Spatial regression modelling was used to build an explanatory model for the occurrence of VL-HIV coinfection within NRB. A total of 1550 cases of VL-HIV coinfection were confirmed. We observed a higher prevalence among males (1232; 83%), individuals aged from 20 to 59 years (850; 54.8%), non-white skin color (1,422; 91.7%), and with low education (550; 35.48%). NRB showed an increasing and significant trend in the detection rate of coinfection (APC, 5.3; 95% CI, 1.4 to 9.4). The states of Maranhão and Piauí comprised the high-risk cluster. The SDH that most correlated with the occurrence of coinfection were poor housing, low income, and low education. VL-HIV is dispersed in the NRB but chiefly affects states with greater social vulnerability. Taken together, these findings reinforce the necessity to implement surveillance strategies that will contribute to the reduction of cases in these populations.

KW - Epidemiology

KW - Neglected diseases

KW - Spatial analysis

KW - Spatial regression

UR - http://www.scopus.com/inward/record.url?scp=85124556441&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85124556441&partnerID=8YFLogxK

U2 - 10.1007/s00436-022-07450-6

DO - 10.1007/s00436-022-07450-6

M3 - Article

C2 - 35142927

AN - SCOPUS:85124556441

SN - 0932-0113

VL - 121

SP - 1021

EP - 1031

JO - Parasitology Research

JF - Parasitology Research

IS - 3

ER -

Magnitude of visceral leishmaniasis and HIV coinfection and association with social determinants of health in the Northeast region of Brazil: a retrospective, spatiotemporal model (2010–2018)

Abstract

Bibliographical note

Keywords

UN SDGs

Publisher link

Find It

Other files and links

Fingerprint

Cite this