Abstract
Magnetoresistive (MR) biosensors are devices designed for the recognition and quantification of magnetic nanoparticles (MNPs) labeled biomolecules. MNPs possess inherent stability, and their magnetic signals remain unmatched by any substances present in the biological sample. Consequently, MR biosensors excel in delivering high sensitivity, minimal background noise, and robust stability, setting them apart from other biosensor types. The two primary MR biosensor variants, based on giant magnetoresistance (GMR) and tunnel magnetoresistance (TMR), exhibit great potential in biological detections, including protein and DNA detection, and genotyping. Recent advancements in nanofabrication technologies have facilitated the miniaturization and cost-effective production of MR biosensors, positioning them as promising candidates for point-of-care testing (POCT). Ongoing research in flexible biosensors further extends their utility to in vivo or on-body diagnostics, enhancing their overall robustness. With these capabilities, MR biosensors have the potential to significantly impact healthcare practices and contribute to improved food safety regulation and environmental monitoring.
| Original language | English (US) |
|---|---|
| Title of host publication | Magnetic Nanoparticles in Nanomedicine |
| Publisher | Elsevier |
| Pages | 289-322 |
| Number of pages | 34 |
| ISBN (Electronic) | 9780443216688 |
| ISBN (Print) | 9780443216695 |
| DOIs | |
| State | Published - Jan 1 2024 |
Bibliographical note
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Keywords
- Biosensors
- biological detection
- flexible sensors
- giant magnetoresistance
- mangetic nanoparticles
- point-of-care testing
- tunnel magnetoresistance