Magnetically-oriented tissue-equivalent tubes: application to a circumferentially-oriented media-equivalent

Robert T Tranquillo, Tim S. Girton, Bruce A. Bromberek, Greg Triebes, Daniel L Mooradian

Research output: Contribution to conferencePaperpeer-review

1 Scopus citations

Abstract

Circumferential orientation of collagen fibrils in a media-equivalent (ME) was achieved in a simple and effective way using the orienting effect of a strong magnetic field during collagen fibrillogenesis when the ME was first created (Tranquillo, et al). Circumferential orientation of the entrapped smooth muscle cells (SMC) was achieved subsequently via previous methods. Evidence of circumferential orientation were observed from ME birefringence and circumferential cell orientation, accelerated ME contraction, and increased stiffness with reduced creep in the circumferential direction. The optimization of the methods to better mimic the circumferential orientation and mechanical properties of a natural media is discussed.

Original languageEnglish (US)
Pages95-96
Number of pages2
StatePublished - Jan 1 1995
EventProceedings of the 1995 Bioengineering Conference - Beever Creek, CO, USA
Duration: Jun 28 1995Jul 2 1995

Other

OtherProceedings of the 1995 Bioengineering Conference
CityBeever Creek, CO, USA
Period6/28/957/2/95

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