Magnetic resonance elastography of intervertebral disc - A new biomarker for disc degeneration

Daniel H. Cortes, Jeremy F. Magland, Alexander C. Wright, Victor H. Barocas, Dawn M. Elliott

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Intervertebral disc degeneration is a cell-mediated process that results in the disruption of its function. These changes are difficult to overturn; consequently, early diagnosis is key for the success of any treatment. Clinically, disc degeneration is diagnosed by analyzing morphological changes characteristic of moderate to advanced stages of degeneration. Therefore, there is a need of a reliable biomarker to characterize the compositional and structural integrity of the disc in early stages of degeneration. In this study, shear modulus is proposed as a new biomarker for disc degeneration and a non-invasive method to measure this mechanical property is presented.

Original languageEnglish (US)
Title of host publication2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012
Pages83-84
Number of pages2
DOIs
StatePublished - Jun 29 2012
Event38th Annual Northeast Bioengineering Conference, NEBEC 2012 - Philadelphia, PA, United States
Duration: Mar 16 2012Mar 18 2012

Publication series

Name2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012

Other

Other38th Annual Northeast Bioengineering Conference, NEBEC 2012
CountryUnited States
CityPhiladelphia, PA
Period3/16/123/18/12

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