Magnetic Nanoparticles Based on CoFe Alloy as T2 MRI Contrast Agents

Oana Georgiana Dragos-Pinzaru, Dumitru Daniel Herea, George Stoian, Firuta Borza, Nicoleta Lupu, Ibro Tabakovic, Daniel Shore, Liliana Savin, Bethanie J.H. Stadler

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Magnetic nanoparticles (MNPs) are playing an increasing role in medical applications, becoming an important tool for cancer detection. In this study, magnetic core-shell CoFe@Au nanowires with optimized biocompatibility, as well as multilayered Au/CoFe/Au nanowires are synthetized by using electrodeposition and electroless-plating techniques. Their morphology and composition are investigated, the materials being tested for their use as T2 contrast agents in MRI. A dramatic increase of r1 and r2 relaxivity values was obtained for the CoFe@Au core-shell nanowires, making these materials best candidates as new MRI contrast agents.

Original languageEnglish (US)
Title of host publication2022 10th E-Health and Bioengineering Conference, EHB 2022
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781665485579
DOIs
StatePublished - 2022
Event10th E-Health and Bioengineering Conference, EHB 2022 - Virtual, Online, Romania
Duration: Nov 17 2022Nov 18 2022

Publication series

Name2022 10th E-Health and Bioengineering Conference, EHB 2022

Conference

Conference10th E-Health and Bioengineering Conference, EHB 2022
Country/TerritoryRomania
CityVirtual, Online
Period11/17/2211/18/22

Bibliographical note

Funding Information:
ACKNOWLEDGMENT This work was supported by the Romanian Ministry of Research, Innovation, and Digitalization under the NUCLEU programme, project PN 19 28 01 01 and by a grant of the Ministry of Research, Innovation and Digitalization, CNCS-UEFISCDI, project number Project PN-III-P4-PCE-2021-1395/GreenEn, within PNCDI III.

Funding Information:
This work was supported by the Romanian Ministry of Research, Innovation, and Digitalization under the NUCLEU programme, project PN 19 28 01 01 and by a grant of the Ministry of Research, Innovation and Digitalization, CNCSUEFISCDI, project number Project PN-III-P4-PCE-2021-1395/GreenEn, within PNCDI III.

Publisher Copyright:
© 2022 IEEE.

Keywords

  • biocompatibility
  • contrast agents
  • electrodeposition
  • nanowires

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