Macrophage dependent lymphocyte immunostimulation in cattle infected with Mycobacterium bovis and with Mycobacterium avium

Charles C Muscoplat; C. O. Thoen; A. W. Chen; D. W. Johnson

doi:10.1128/iai.10.3.675-677.1974

Macrophage dependent lymphocyte immunostimulation in cattle infected with Mycobacterium bovis and with Mycobacterium avium

Charles C Muscoplat, C. O. Thoen, A. W. Chen, D. W. Johnson

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Cultures of bovine peripheral blood leukocytes were prepared from calves inoculated with Mycobacterium bovis and with M. avium. Suitable lymphocyte stimulation was obtained with specific and nonspecific mycobacterial mitogens. Leukocyte cultures depleted of adherent, macrophage type cells did not respond to stimulation with purified protein derivative, although they were responsive to phytohemagglutinin.

Original language	English (US)
Pages (from-to)	675-677
Number of pages	3
Journal	Infection and immunity
Volume	10
DOIs	https://doi.org/10.1128/iai.10.3.675-677.1974
State	Published - 1974

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title = "Macrophage dependent lymphocyte immunostimulation in cattle infected with Mycobacterium bovis and with Mycobacterium avium",

abstract = "Cultures of bovine peripheral blood leukocytes were prepared from calves inoculated with Mycobacterium bovis and with M. avium. Suitable lymphocyte stimulation was obtained with specific and nonspecific mycobacterial mitogens. Leukocyte cultures depleted of adherent, macrophage type cells did not respond to stimulation with purified protein derivative, although they were responsive to phytohemagglutinin.",

author = "Muscoplat, {Charles C} and Thoen, {C. O.} and Chen, {A. W.} and Johnson, {D. W.}",

year = "1974",

doi = "10.1128/iai.10.3.675-677.1974",

language = "English (US)",

volume = "10",

pages = "675--677",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

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T1 - Macrophage dependent lymphocyte immunostimulation in cattle infected with Mycobacterium bovis and with Mycobacterium avium

AU - Muscoplat, Charles C

AU - Thoen, C. O.

AU - Chen, A. W.

AU - Johnson, D. W.

PY - 1974

Y1 - 1974

N2 - Cultures of bovine peripheral blood leukocytes were prepared from calves inoculated with Mycobacterium bovis and with M. avium. Suitable lymphocyte stimulation was obtained with specific and nonspecific mycobacterial mitogens. Leukocyte cultures depleted of adherent, macrophage type cells did not respond to stimulation with purified protein derivative, although they were responsive to phytohemagglutinin.

AB - Cultures of bovine peripheral blood leukocytes were prepared from calves inoculated with Mycobacterium bovis and with M. avium. Suitable lymphocyte stimulation was obtained with specific and nonspecific mycobacterial mitogens. Leukocyte cultures depleted of adherent, macrophage type cells did not respond to stimulation with purified protein derivative, although they were responsive to phytohemagglutinin.

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DO - 10.1128/iai.10.3.675-677.1974

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