Lysozyme Levels in Middle Ear Effusion and Serum in Otitis Media

Teruhiko Harada, Steven S Juhn, George L. Adams

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Lysozyme concentrations in middle ear effusion and serum were determined in patients with otitis media with effusion. Lysozyme concentrations in middle ear effusion were significantly higher than in serum. Children with mucoid otitis media showed significantly higher levels of lysozyme in middle ear effusion than children with serous otitis media and adults with otitis media with effusion. Higher levels of lysozyme were observed in the group of children younger than 5 years old compared with the age group of 6- to 10year-olds. Lysozyme concentrations of middle ear effusion in adults were significantly lower than those of mucoid otitis media in children. These results indicate that lysozyme plays an important role in the disease process of otitis media. (Arch Otolaryngol Head Neck Surg. 1990;116:54-56)

Original languageEnglish (US)
Pages (from-to)54-56
Number of pages3
JournalArchives of Otolaryngology--Head and Neck Surgery
Volume116
Issue number1
DOIs
StatePublished - Jan 1990

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