Lymphocyte interactions with endothelial cells

Yoji Shimizu, Walter Newman, Yoshiya Tanaka, Stephen Shaw

Research output: Contribution to journalReview articlepeer-review

716 Scopus citations


Adhesion of lymphocytes to endothelium is vital to lymphocyte migration into lymphoid tissue and into inflammatory sites. In this review, Yoji Shimizu and colleagues identify the molecules that mediate lymphocyte-endothelial cell adhesion, describe the underlying principles of lymphocyte migration, and discuss a model of the sequence of events that allow a lymphocyte to successfully attach to endothelium and migrate into the surrounding tissue.

Original languageEnglish (US)
Pages (from-to)106-112
Number of pages7
JournalImmunology Today
Issue number3
StatePublished - 1992

Bibliographical note

Funding Information:
We apologize that proper acknowledgment <)f all of the contributions made by investigators in this field was not possible. Yoli Shimizu i~ supported by NIH grant AI31126, and an American Cancer Society Junior Faculty Research Award.


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