Lymph node with extensive involvement by Cryptococcus shortly following liver transplantation

Scott R. Gilles, Sophie S. Arbefeville, Patricia Ferrieri, Elizabeth L. Courville

Research output: Contribution to journalArticle

Abstract

Herein, we present a case of extensive lymph node involvement by disseminated Cryptococcus infection developing in the immediate period after liver transplantation and initiation of immunosuppressive therapy. The patient, a 56 year old ethnicity unknown man, received a liver transplant for acute decompensated liver. Beginning 24 days after transplantation, he was found to have Cryptococcus neoformans infection, involving the pleural fluid, blood, cerebrospinal fluid (CSF), liver, and lymph nodes. He received treatment with amphotericin B and flucytosine; he was transitioned to fluconazole, and his response was good. This relatively rapid development of disease raises the possibility of donor-derived Cryptococcus infection.

Original languageEnglish (US)
Pages (from-to)E78-E81
JournalLab Medicine
Volume49
Issue number3
DOIs
StatePublished - Aug 1 2018

Fingerprint

Cryptococcus
Liver
Liver Transplantation
Lymph Nodes
Infection
Flucytosine
Cryptococcus neoformans
Fluconazole
Amphotericin B
Immunosuppressive Agents
Cerebrospinal fluid
Transplants
Cerebrospinal Fluid
Transplantation
Tissue Donors
Blood
Therapeutics
Fluids

Keywords

  • Biopsy
  • Cryptococcus
  • Immunosuppressive therapy
  • Infection
  • Liver transplant
  • Lymph node

Cite this

Lymph node with extensive involvement by Cryptococcus shortly following liver transplantation. / Gilles, Scott R.; Arbefeville, Sophie S.; Ferrieri, Patricia; Courville, Elizabeth L.

In: Lab Medicine, Vol. 49, No. 3, 01.08.2018, p. E78-E81.

Research output: Contribution to journalArticle

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