Abstract
Locoregional spread of melanoma to its draining lymph node basin is the strongest negative prognostic factor for patients. Exclusive of clinical trials, patients with sentinel lymph node-positive (microscopic) or clinically palpable (macroscopic) nodal disease should undergo lymphadenectomy. This article reviews the management and technical aspects of surgical care for regional metastases. Adjunct therapies (immunotherapy, targeted therapy, and radiation) may supplement lymphadenectomy in certain patient populations. Surgical morbidity after lymphadenectomy can be substantial, creating opportunities for improvement via minimally invasive techniques or refined patient selection.
Original language | English (US) |
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Pages (from-to) | 261-277 |
Number of pages | 17 |
Journal | Surgical Oncology Clinics of North America |
Volume | 24 |
Issue number | 2 |
DOIs | |
State | Published - Apr 1 2015 |
Bibliographical note
Publisher Copyright:© 2015 Elsevier Inc.
Keywords
- Locoregional spread
- Lymphadenectomy
- Stage III melanoma
- Videoscopic inguinal lymphadenectomy