Lyme neuroborreliosis presenting as Alice in Wonderland syndrome

Ibrahim M. Binalsheikh, David Griesemer, Sonya Wang, Rebeca Alvarez-Altalef

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


We describe a 7-year-old boy with Alice in Wonderland syndrome associated with Lyme disease. He presented with metamorphopsia and auditory hallucinations in the absence of previous tick bites or other signs of Lyme disease. The boy never developed clinical seizures, and electroencephalograms during these spells indicated no epileptic activity. There was no history of migraine. Cranial magnetic resonance imaging produced normal results. Lyme serology tested positive in both serum and cerebrospinal fluid. He was treated with intravenous ceftriaxone for 3 weeks, with complete resolution of signs. This case report is the first, to our knowledge, of neuroborreliosis presenting as Alice in Wonderland syndrome with complete resolution of findings after intravenous antibiotic treatment.

Original languageEnglish (US)
Pages (from-to)185-186
Number of pages2
JournalPediatric Neurology
Issue number3
StatePublished - Mar 2012
Externally publishedYes

Bibliographical note

Copyright 2012 Elsevier B.V., All rights reserved.


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