Lung cancer in chromate-exposed aerospace workers

Bruce H. Alexander, Harvey Checkoway, Laurence Wechsler, Nicholas J. Heyer, J. Michael Muhm, Thomas P. O'Keeffe

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

A retrospective cohort study evaluated the risk of lung cancer in aerospace workers with a minimum of 6 months' employment in jobs with chromium [VI] exposure (n = 2429). Standardized incidence ratios (SIR) estimated the risk of lung cancer by duration of employment in chromate- exposure jobs and cumulative exposure based on industrial hygiene and work- history data. The overall SIR for lung cancer was 0.8 (observed [Obs] = 15]. Lung cancer risk was inversely related to estimates of cumulative chromate exposure and duration of employment as a painter. Although based on few cases, an elevated lung cancer risk was found in subjects who had worked for 5 or more years as a chrome plater or surface processor tank tender (Obs = 2, SIR = 1.9) and sander/masker or polisher (Obs = 3, SIR = 2.7). A clear association was not observed between chromate exposure and the risk of lung cancer in this population of workers.

Original languageEnglish (US)
Pages (from-to)1253-1258
Number of pages6
JournalJournal of occupational and environmental medicine
Volume38
Issue number12
DOIs
StatePublished - Dec 1 1996

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