Lung and heart allocation in the United States

M. Colvin-Adams, M. Valapour, Marshall I Hertz, B. Heubner, K. Paulson, V. Dhungel, M. A. Skeans, L. Edwards, V. Ghimire, C. Waller, W. S. Cherikh, Bert L Kasiske, J. J. Snyder, A. K. Israni

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Lung and heart allocation in the United States has evolved over the past 20-30 years to better serve transplant candidates and improve organ utilization. The current lung allocation policy, based on the Lung Allocation Score, attempts to take into account risk of death on the waiting list and chance of survival posttransplant. This policy is flexible and can be adjusted to improve the predictive ability of the score. Similarly, in response to the changing clinical phenotype of heart transplant candidates, heart allocation policies have evolved to a multitiered algorithm that attempts to prioritize organs to the most infirm, a designation that fluctuates with trends in therapy. The Organ Procurement and Transplantation Network and its committees have been responsive, as demonstrated by recent modifications to pediatric heart allocation and mechanical circulatory support policies and by ongoing efforts to ensure that heart allocation policies are equitable and current. Here we examine the development of US lung and heart allocation policy, evaluate the application of the current policy on clinical practice and explore future directions for lung and heart allocation.

Original languageEnglish (US)
Pages (from-to)3213-3234
Number of pages22
JournalAmerican Journal of Transplantation
Volume12
Issue number12
DOIs
StatePublished - Dec 1 2012

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Lung
Transplants
Tissue and Organ Procurement
Waiting Lists
Organ Transplantation
Pediatrics
Phenotype
Therapeutics

Keywords

  • Heart allograft
  • lung allograft
  • organ allocation
  • transplant waiting list
  • transplantation

Cite this

Colvin-Adams, M., Valapour, M., Hertz, M. I., Heubner, B., Paulson, K., Dhungel, V., ... Israni, A. K. (2012). Lung and heart allocation in the United States. American Journal of Transplantation, 12(12), 3213-3234. https://doi.org/10.1111/j.1600-6143.2012.04258.x

Lung and heart allocation in the United States. / Colvin-Adams, M.; Valapour, M.; Hertz, Marshall I; Heubner, B.; Paulson, K.; Dhungel, V.; Skeans, M. A.; Edwards, L.; Ghimire, V.; Waller, C.; Cherikh, W. S.; Kasiske, Bert L; Snyder, J. J.; Israni, A. K.

In: American Journal of Transplantation, Vol. 12, No. 12, 01.12.2012, p. 3213-3234.

Research output: Contribution to journalArticle

Colvin-Adams, M, Valapour, M, Hertz, MI, Heubner, B, Paulson, K, Dhungel, V, Skeans, MA, Edwards, L, Ghimire, V, Waller, C, Cherikh, WS, Kasiske, BL, Snyder, JJ & Israni, AK 2012, 'Lung and heart allocation in the United States', American Journal of Transplantation, vol. 12, no. 12, pp. 3213-3234. https://doi.org/10.1111/j.1600-6143.2012.04258.x
Colvin-Adams M, Valapour M, Hertz MI, Heubner B, Paulson K, Dhungel V et al. Lung and heart allocation in the United States. American Journal of Transplantation. 2012 Dec 1;12(12):3213-3234. https://doi.org/10.1111/j.1600-6143.2012.04258.x
Colvin-Adams, M. ; Valapour, M. ; Hertz, Marshall I ; Heubner, B. ; Paulson, K. ; Dhungel, V. ; Skeans, M. A. ; Edwards, L. ; Ghimire, V. ; Waller, C. ; Cherikh, W. S. ; Kasiske, Bert L ; Snyder, J. J. ; Israni, A. K. / Lung and heart allocation in the United States. In: American Journal of Transplantation. 2012 ; Vol. 12, No. 12. pp. 3213-3234.
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