Mechanisms of salivary lubrication can be quantitatively measured by a reduction in the coefficient of friction. It is important that lubrication be assessed under the conditions of the oral cavity to properly assess lubrication regimes. The relative lubricity of three artificial salivas and two controls were assessed at a bovine enamel interface in an artificial mouth with a range of conditions that approximate oral function. Statistical analysis indicated that the enamel lubricity of sodium dodecylsulfate (SDS) and Oracare-D saliva substitutes were different from the other saliva substitutes and water. The low friction with Oracare-D and SDS saliva substitutes was because of resident amphipaths adsorbed at the enamel interface. Amphipaths adsorbed on enamel may provide a reduction in interocculsal friction and its resulting complications for patients with xerostomia.
Bibliographical noteFunding Information:
Three basic lubrication regimes are recognized: thick film, boundary lubrication, and a mixture of these two re- This investigation was supported in part by USPHS grant DE08240 from the National Institute of Dental Research, Na-tional Institutes of Health, Bethesda, Md. aVolunteer Associate Professor, Minnesota Dental Research Cen-ter for Biomaterials and Biomechanics, Department of Oral Bi-ology, School of Dentistry, University of Minnesota. bHarvey L. Anderson Endowed Professor, and Director, Minne-sota Dental Research Center for Biomaterials and Biomechan-its, Department of Oral Biology, School of Dentistry, University of Minnesota. “Professor, Department of Oral Biology, Dental Research Institute, School of Dental Medicine, State University of New York at Buffalo.