Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis

Liyuan Ran, Xiaoshuang Wang, Ai Mi, Yanshuang Liu, Jin Wu, Haoan Wang, Meihua Guo, Jie Sun, Bo Liu, Youwei Li, Dan Wang, Rujiao Jiang, Ning Wang, Wenting Gao, Li Zeng, Lin Huang, Xiaoli Chen, Derek LeRoith, Bin Liang, Xin LiYingjie Wu

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Physiology; Cellular Physiology; Endocrinology; Diabetology

Original languageEnglish (US)
Pages (from-to)106-121
Number of pages16
JournaliScience
Volume16
DOIs
StatePublished - Jun 28 2019

Bibliographical note

Funding Information:
This work was supported by the National Natural Science Foundation of China (No. 81600668 ; No. 81471000l ); the Ministry of Science and Technology of China (No. 2014DFA32120 ); and Research Project of Educational Commission of Liaoning , China (No. L2016023 ).

Funding Information:
This work was supported by the National Natural Science Foundation of China (No. 81600668; No. 81471000l); the Ministry of Science and Technology of China (No. 2014DFA32120); and Research Project of Educational Commission of Liaoning, China (No.L2016023). Y.W. and L.R. conceived the study, designed the experiments, and wrote the manuscript. L.R. and X.W. performed experiments and collected and analyzed data. A.M. Y.L. and H.W. performed cold and cell experiments. J.W. J.S. and B.L. assisted with the qPCR and western Blot. M.G. D.W. W.G. and Y.L. performed animal breeding. R.J. and N.W. assisted with histological experiments. L.Z. L.H. X.C. B.L. and X.L. also designed the experiments and involved in discussion and writing the manuscript. L.Z. D.L. and X.L. provided language help. All authors reviewed the manuscript. The authors declare no competing interests.

Keywords

  • Cellular Physiology
  • Diabetology
  • Endocrinology
  • Physiology

Fingerprint Dive into the research topics of 'Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis'. Together they form a unique fingerprint.

Cite this