Longitudinal Trajectories of Alcohol Use in Vietnamese Adults with Hazardous Alcohol Use and HIV

M. Kumi Smith, Carl A. Latkin, Heidi E. Hutton, Geetanjali Chander, Eva A. Enns, Tran Viet Ha, Constantine Frangakis, Teerada Sripaipan, Vivian F. Go

Research output: Contribution to journalArticlepeer-review


A three-armed drinking cessation trial in Vietnam found that both a brief and intensive version of an intervention effectively reduced hazardous drinking in people living with HIV. We used group-based trajectory modeling (GBTM) to assess the extent to which findings may vary by latent subgroups distinguished by their unique responses to the intervention. Using data on drinking patterns collected over the 12 months, GBTM identified five trajectory groups, three of which were suboptimal [“non-response” (17.2%); “non-sustained response” (15.7%), “slow response” (13.1%)] and two optimal [“abstinent” (36.4%); “fast response” (17.6%)]. Multinomial logistic regression was used to determine that those randomized to any intervention arm were less likely to be in a suboptimal trajectory group, even more so if randomized to the brief (vs. intensive) intervention. Older age and higher baseline coping skills protected against membership in suboptimal trajectory groups; higher scores for readiness to quit drinking were predictive of it. GBTM revealed substantial heterogeneity in participants’ response to a cessation intervention and may help identify subgroups who may benefit from more specialized services within the context of the larger intervention.

Original languageEnglish (US)
Pages (from-to)1972-1980
Number of pages9
JournalAIDS and Behavior
Issue number6
StatePublished - Jun 2023

Bibliographical note

Funding Information:
Primary funding was obtained from the National Institute on Drug Abuse of the National Institutes of Health (Grant No. R01DA037440).

Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.


  • Alcohol cessation
  • People living with HIV
  • People who inject drugs
  • Trajectory modeling
  • Vietnam


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