Long-term storage of gametes and gonadal tissues at room temperatures: the end of the ice age?

Pierre Comizzoli, Pasqualino Loi, Pasquale Patrizio, Allison Hubel

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Long-term preservation of viable spermatozoa, eggs, embryos, and gonadal tissues of good quality is essential in human reproductive medicine and for the population management of livestock, laboratory, and wild species. Instead of using freezing temperatures, encouraging findings indicate that structures and functions of gametes or gonadal tissues can be suspended in trehalose glass after dehydration and then preserved at supra-zero temperatures. As a new era in fertility preservation and biobanking is about to start, the advantages, needs, and implications of germplasm storage at room temperatures must be carefully examined. Although very promising, the development of alternate biobanking strategies does not necessarily mean that the end of the “ice age” (cryopreservation) is near.

Original languageEnglish (US)
Pages (from-to)321-325
Number of pages5
JournalJournal of Assisted Reproduction and Genetics
Issue number2
StatePublished - Feb 2022

Bibliographical note

Publisher Copyright:
© 2022, This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.


  • Anhydrobiosis
  • Biobanking
  • Cryopreservation
  • Freezing temperatures
  • Room temperature storage

PubMed: MeSH publication types

  • Journal Article


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