Long-term brain and behavioral consequences of early iron deficiency

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215 Scopus citations


Early iron deficiency not only affects brain and behavioral function during the period of iron deficiency, it persists long after treatment. The mechanisms include long-term alterations in dopamine metabolism, myelination, and hippocampal structure and function. Recent studies have demonstrated long-term genomic changes, which suggests the regulation of brain function is fundamentally altered.

Original languageEnglish (US)
Pages (from-to)S43-S48
JournalNutrition reviews
Issue numberSUPPL. 1
StatePublished - Nov 2011


  • Early iron deficiency
  • Long-term iron alterations
  • Long-term iron genomic changes


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