Long-Term Body Composition Changes in Women Following Roux-en-Y Gastric Bypass Surgery

Abigail J Johnson, Adam J. Kuchnia, Lauren M. Beckman, Cyrus Jahansouz, Jennifer R. Mager, Shalamar Sibley, Carrie P Earthman

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Background: Although most individuals experience successful weight loss following Roux-en-Y gastric bypass (RYGB), weight regain is a concern, the composition of which is not well documented. Our aim was to evaluate changes in body composition and handgrip strength as a measure of functional status in participants from a previous 1-year post-RYGB longitudinal study who had undergone RYGB approximately 9 years prior. Methods: Five women from an original larger cohort were monitored pre-RYGB and 1.5 months, 6 months, 1 year, and 9 years post-RYGB. Body composition was assessed at all time points using dual energy x-ray absorptiometry and multiple dilution. Handgrip strength was measured using a digital isokinetic hand dynamometer (Takei Scientific Instruments, Ltd, Tokyo, Japan). Results: Mean time to final follow-up was 8.7 years. Lean soft tissue (LST) loss over the ∼9-year period was on average 11.9 ± 5.6 kg. Compared with 1-year post-RYGB, 9-year LST was 4.4 ± 3.0 kg lower (P =.03). Fat-free mass decreased over the 9-year period by 12.6 ± 5.8 kg. Mean fat mass (FM) decreased from 75.4 ± 22.6 kg pre-RYGB to 35.5 ± 21.5 kg 1 year post-RYGB but then trended toward an increase of 8.6 ± 7.0 kg between 1 year and 9 years post-RYGB (P =.053). Loss of LST was correlated with loss of handgrip strength (r = 0.64, P =.0005). Conclusion: The continued loss of lean mass associated with decreased handgrip strength occurring with long-term trend toward FM regain post-RYGB is concerning. The loss of LST and functional strength carries particular implications for the aging bariatric population and should be investigated further.

Original languageEnglish (US)
Pages (from-to)583-591
Number of pages9
JournalJournal of Parenteral and Enteral Nutrition
Volume41
Issue number4
DOIs
StatePublished - May 1 2017

Keywords

  • Roux-en-Y gastric bypass
  • bariatric
  • dual-energy x-ray absorptiometry
  • fat-free mass
  • handgrip strength
  • lean body mass
  • lean tissue
  • obesity

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