Long ascending projections from substantia gelatinosa Rolandi and the subjacent dorsal horn in the rat

Glenn J. Giesler, J. Timothy Cannon, Gideon Urca, John C. Liebeskind

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

Small neurons of the substantia gelatinosa Rolandi and the subjacent dorsal horn of the spinal cord have been thought to exert a direct modulatory effect only on neurons located within a distance of a few spinal segments. By using the technique of retrograde transport of horseradish peroxidase, however, it has been found that in the rat a significant number of these cells, particularly those of the subjacent dorsal horn, ascend many spinal segments to the lateral cervical nucleus and to the lower brainstem. These data provide an anatomic basis for a role of substantia gelatinosa Rolandi and subjacent dorsal horn cells in modulating or contributing to sensory information transmission not only in nearby segments but in far distant structures.

Original languageEnglish (US)
Pages (from-to)984-986
Number of pages3
JournalScience
Volume202
Issue number4371
DOIs
StatePublished - 1978

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