Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients

  • Jennifer Williams
  • , Harlan R Sayles
  • , Jane L Meza
  • , Patrick Sayre
  • , Uriel Sandkovsky
  • , Howard E Gendelman
  • , Charles Flexner
  • , Susan Swindells

Research output: Contribution to journalArticlepeer-review

95 Scopus citations

Abstract

AIM: To gauge patient interest in receiving long-acting injectable nanoformulated antiretroviral therapy.

METHODS: Four hundred adult HIV-infected patients currently prescribed antiretroviral therapy were surveyed. χ(2) tests were used for comparisons of interest across groups.

RESULTS: Respondents were 68% male and 53% African-American, with a mean age of 47 years. Overall, 73% of patients indicated that they would definitely or probably try injectable nanoformulated antiretroviral therapy; 61% with weekly dosing; 72% every 2 weekly; and 84% monthly. In total, 48% indicated that they were very concerned about the possible side effects and 35% were very concerned about needle use.

CONCLUSION: The majority of respondents indicated that they definitely or probably would try parenteral nanoformulated antiretroviral therapy.

Original languageEnglish (US)
Pages (from-to)1807-13
Number of pages7
JournalNanomedicine
Volume8
Issue number11
DOIs
StatePublished - Nov 2013
Externally publishedYes

Keywords

  • Adolescent
  • Adult
  • Aged
  • Anti-HIV Agents/therapeutic use
  • Female
  • HIV Infections/drug therapy
  • Humans
  • Male
  • Middle Aged
  • Patient Acceptance of Health Care/statistics & numerical data
  • Young Adult

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

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