Locoregional treatment of breast cancer in women with and without preoperative magnetic resonance imaging

Elissa M. Ozanne, Julie E. Weiss, Tracy Onega, Wendy DeMartini, Karla Kerlikowske, Diana S M Buist, Louise Henderson, Rebecca A. Hubbard, Martha Goodrich, Anna N A Tosteson, Beth A. Virnig, Cristina O'Donoghue

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Background Preoperative magnetic resonance imaging (MRI) use has increased among older women diagnosed with breast cancer. MRI detects additional malignancy, but its impact on locoregional surgery and radiation treatment remains unclear. Methods We examined the associations of preoperative MRI with initial locoregional treatment type (mastectomy, breast conserving surgery [BCS] with radiation therapy [RT], and BCS without RT) and BCS reoperation rates for Surveillance, Epidemiology, and End Results Medicare women diagnosed with stages 0 to III breast cancer from 2005 to 2009 (n = 55,997). Results We found no association of initial locoregional treatment of mastectomy (odds ratios [OR], 1.04; 95% confidence intervals,.98 to 1.11) or reoperation after initial BCS (OR,.96; 95% confidence intervals,.89 to 1.03) between women with preoperative MRI (16.2%) compared to women without MRI. However, women with MRI who had initial BCS were more likely to undergo RT (OR, 1.09 [1.02 to 1.16]). Conclusions Preoperative breast MRI in Medicare-enrolled women with stages 0 to III breast cancer was not associated with increased mastectomy. However, in older women with MRI undergoing BCS, there was a greater use of RT.

Original languageEnglish (US)
Pages (from-to)132-139.e2
JournalAmerican journal of surgery
Issue number1
StatePublished - Jan 1 2017

Bibliographical note

Publisher Copyright:
© 2016


  • Breast cancer
  • Breast conserving surgery
  • Mastectomy
  • Preoperative MRI


Dive into the research topics of 'Locoregional treatment of breast cancer in women with and without preoperative magnetic resonance imaging'. Together they form a unique fingerprint.

Cite this