Localized retroperitoneal fibromatosis causing intestinal obstruction in a cynomolgus monkey (Macaca fascicularis).

J. D. Fikes, M. G. O'Sullivan

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Gross examination of a 24-month-old, male cynomolgus monkey (Macaca fascicularis) revealed obstruction of the ileum by a mass that entrapped and compressed the ileocecal junction. The mass was well circumscribed, firm, and white on cut surface. Histologically, the mass consisted of spindle-shaped cells arranged in interweaving bundles or as narrow cords and individual cells widely separated by dense collagen. A diagnosis of localized retroperitoneal fibromatosis was made based on the characteristic gross and microscopic findings and isolation of type D simian retrovirus, serotype-2, from spleen and mesenteric lymph node. Monkeys with localized retroperitoneal fibromatosis generally exhibit signs only of a palpable mass at the ileocecal junction and/or nonspecific diarrhea. This case represents an unusual presentation of localized retroperitoneal fibromatosis in which the lesion produced intestinal obstruction and death.

Original languageEnglish (US)
Pages (from-to)713-716
Number of pages4
JournalVeterinary pathology
Volume32
Issue number6
DOIs
StatePublished - Nov 1995

Fingerprint

Dive into the research topics of 'Localized retroperitoneal fibromatosis causing intestinal obstruction in a cynomolgus monkey (Macaca fascicularis).'. Together they form a unique fingerprint.

Cite this