Recent improvements in the immunofluorescence technique have made possible the localization of dopamine-β-hydroxylase in neuron cell bodies, axon fibers and terminal fibers in brain. This technique compares favorably with the Falck and Hillarp histofluorescence technique for visualization of catecholamines. The immunofluorescence technique has several advantages that make it more applicable to post-mortem tissue. Preliminary results of dopamine-β-hydroxylase localization in human brain are presented.
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* This work was supported by Grants No. MH-21874, DA-00259, DA-00209 and a Research Scientist Development Award MH-70451.
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