Abstract
Antisera to histamine were generated by immunization of albino guinea pigs with a complex of histamine and methylated-bovine serum albumin. Characterization of the antisera and preliminary mapping of histaminergic neurons were conducted on brain tissue from normal and experimentally manipulated rats. Using immunofluorescence, histamine-like immunoreactive cell bodies were revealed in the lateral hypothalamus, and fibers were stained in the hypothalamus, cortex, amygdala and hippocampus.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 105-110 |
| Number of pages | 6 |
| Journal | Neuroscience Letters |
| Volume | 29 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 16 1982 |
Keywords
- antiserum
- colchicine
- histamine
- hypothalamus
- immunofluorescence