Localization of neuronal histamine in rat brain

Barbara J. Wilcox, Virginia S Seybold

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

Antisera to histamine were generated by immunization of albino guinea pigs with a complex of histamine and methylated-bovine serum albumin. Characterization of the antisera and preliminary mapping of histaminergic neurons were conducted on brain tissue from normal and experimentally manipulated rats. Using immunofluorescence, histamine-like immunoreactive cell bodies were revealed in the lateral hypothalamus, and fibers were stained in the hypothalamus, cortex, amygdala and hippocampus.

Original languageEnglish (US)
Pages (from-to)105-110
Number of pages6
JournalNeuroscience Letters
Volume29
Issue number2
DOIs
StatePublished - Apr 16 1982

Fingerprint

Histamine
Immune Sera
Brain
Lateral Hypothalamic Area
Amygdala
Hypothalamus
Fluorescent Antibody Technique
Immunization
Hippocampus
Guinea Pigs
Neurons
Cell Body
methylated bovine serum albumin

Keywords

  • antiserum
  • colchicine
  • histamine
  • hypothalamus
  • immunofluorescence

Cite this

Localization of neuronal histamine in rat brain. / Wilcox, Barbara J.; Seybold, Virginia S.

In: Neuroscience Letters, Vol. 29, No. 2, 16.04.1982, p. 105-110.

Research output: Contribution to journalArticle

Wilcox, Barbara J. ; Seybold, Virginia S. / Localization of neuronal histamine in rat brain. In: Neuroscience Letters. 1982 ; Vol. 29, No. 2. pp. 105-110.
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