Localization of chromosomal RNA in human G-banded metaphase chromosomes

Mary Ella M Pierpont; Jorge J. Yunis

doi:10.1016/0014-4827(77)90176-8

Localization of chromosomal RNA in human G-banded metaphase chromosomes

Mary Ella M Pierpont, Jorge J. Yunis

Pediatric Genetics & Metabolism

Research output: Contribution to journal › Article › peer-review

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Abstract

Chromosomal RNA with an 11% dihydropyrimidine content was extracted from human placental chromatin. Under appropriate conditions, this RNA showed wide-spread in situ hybridization to metaphase chromosomes. This included preferential hybridization to the telomeric regions and heterochromatic short arms of acrocentric chromosomes as well as significant hybridization to Q- and G-positive bands.

Original language	English (US)
Pages (from-to)	303-308
Number of pages	6
Journal	Experimental Cell Research
Volume	106
Issue number	2
DOIs	https://doi.org/10.1016/0014-4827(77)90176-8
State	Published - May 1977

Bibliographical note

Funding Information:
This study was supported in part by Grants HD 01962 and GM 00025 from the NIH.

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10.1016/0014-4827(77)90176-8

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title = "Localization of chromosomal RNA in human G-banded metaphase chromosomes",

abstract = "Chromosomal RNA with an 11% dihydropyrimidine content was extracted from human placental chromatin. Under appropriate conditions, this RNA showed wide-spread in situ hybridization to metaphase chromosomes. This included preferential hybridization to the telomeric regions and heterochromatic short arms of acrocentric chromosomes as well as significant hybridization to Q- and G-positive bands.",

author = "Pierpont, {Mary Ella M} and Yunis, {Jorge J.}",

note = "Funding Information: This study was supported in part by Grants HD 01962 and GM 00025 from the NIH.",

year = "1977",

month = may,

doi = "10.1016/0014-4827(77)90176-8",

language = "English (US)",

volume = "106",

pages = "303--308",

journal = "Experimental Cell Research",

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T1 - Localization of chromosomal RNA in human G-banded metaphase chromosomes

AU - Pierpont, Mary Ella M

AU - Yunis, Jorge J.

N1 - Funding Information: This study was supported in part by Grants HD 01962 and GM 00025 from the NIH.

PY - 1977/5

Y1 - 1977/5

N2 - Chromosomal RNA with an 11% dihydropyrimidine content was extracted from human placental chromatin. Under appropriate conditions, this RNA showed wide-spread in situ hybridization to metaphase chromosomes. This included preferential hybridization to the telomeric regions and heterochromatic short arms of acrocentric chromosomes as well as significant hybridization to Q- and G-positive bands.

AB - Chromosomal RNA with an 11% dihydropyrimidine content was extracted from human placental chromatin. Under appropriate conditions, this RNA showed wide-spread in situ hybridization to metaphase chromosomes. This included preferential hybridization to the telomeric regions and heterochromatic short arms of acrocentric chromosomes as well as significant hybridization to Q- and G-positive bands.

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AN - SCOPUS:0017687660

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JF - Experimental Cell Research

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ER -

Localization of chromosomal RNA in human G-banded metaphase chromosomes

Abstract

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