Localization of chromosomal RNA in human G-banded metaphase chromosomes

Mary Ella M Pierpont, Jorge J. Yunis

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Chromosomal RNA with an 11% dihydropyrimidine content was extracted from human placental chromatin. Under appropriate conditions, this RNA showed wide-spread in situ hybridization to metaphase chromosomes. This included preferential hybridization to the telomeric regions and heterochromatic short arms of acrocentric chromosomes as well as significant hybridization to Q- and G-positive bands.

Original languageEnglish (US)
Pages (from-to)303-308
Number of pages6
JournalExperimental Cell Research
Issue number2
StatePublished - May 1977

Bibliographical note

Funding Information:
This study was supported in part by Grants HD 01962 and GM 00025 from the NIH.


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