Local migration promotes competitive restraint in a host-pathogen 'tragedy of the commons'

Benjamin Kerr, Claudia Neuhauser, Brendan J.M. Bohannan, Antony M. Dean

Research output: Contribution to journalArticlepeer-review

301 Scopus citations

Abstract

Fragmented populations possess an intriguing duplicity: even if subpopulations are reliably extinction-prone, asynchrony in local extinctions and recolonizations makes global persistence possible. Migration is a double-edged sword in such cases: too little migration prevents recolonization of extinct patches, whereas too much synchronizes subpopulations, raising the likelihood of global extinction. Both edges of this proverbial sword have been explored by manipulating the rate of migration within experimental populations. However, few experiments have examined how the evolutionary ecology of fragmented populations depends on the pattern of migration. Here, we show that the migration pattern affects both coexistence and evolution within a community of bacterial hosts (Escherichia coli) and viral pathogens (T4 coliphage) distributed across a large network of subpopulations. In particular, different patterns of migration select for distinct pathogen strategies, which we term 'rapacious' and 'prudent'. These strategies define a 'tragedy of the commons': rapacious phage displace prudent variants for shared host resources, but prudent phage are more productive when alone. We find that prudent phage dominate when migration is spatially restricted, while rapacious phage evolve under unrestricted migration. Thus, migration pattern alone can determine whether a de novo tragedy of the commons is resolved in favour of restraint.

Original languageEnglish (US)
Pages (from-to)75-78
Number of pages4
JournalNature
Volume442
Issue number7098
DOIs
StatePublished - Jul 6 2006

Bibliographical note

Funding Information:
Acknowledgements We thank Y. Dang for help in the laboratory and the BioTechnology Resource Center at the University of Minnesota for robot access. We thank S. Abedon, C. Bergstrom, J. Bull, J. Fletcher, K. Koelle, C. Lehman, B. Levin and D. Stephens for useful feedback on this project and manuscript. This work was partially supported by an NSF grant to C.N. and an NIH grant to A.M.D.

Fingerprint

Dive into the research topics of 'Local migration promotes competitive restraint in a host-pathogen 'tragedy of the commons''. Together they form a unique fingerprint.

Cite this