Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules that Enhance Ca²⁺ Transport

Keyphrases

• Living Cells 100%
• Ca2+ Transport 100%
• High-throughput Screening Platform 100%
• SERCA2a 100%
• Drug-like 100%
• Phospholamban 83%
• High-throughput Screening 50%
• Fluorescence Lifetime 33%
• Heart Failure 33%
• Concatenated 33%
• Single-molecule Fluorescence Resonance Energy Transfer (smFRET) 33%
• Complex Structure 16%
• Therapeutic Development 16%
• Small Molecules 16%
• Sarcoplasmic Reticulum 16%
• Fluorescent Protein 16%
• Calcium Uptake 16%
• Polypeptide Chain 16%
• Transmembrane Protein 16%
• Fluorescent Compounds 16%
• Large-scale Screen 16%
• Uptake Assay 16%
• Dual-wavelength 16%
• Fluorescent Sensor 16%
• Heart Failure Medication 16%
• Inhibitory Interactions 16%
• False Positive Hits 16%

Biochemistry, Genetics and Molecular Biology

• Phospholamban 100%
• High Throughput Screening 100%
• Fluorescence Resonance Energy Transfer 40%
• Lifespan 40%
• Small Molecule 20%
• Calcium Transport 20%
• Heart Muscle Potential 20%
• Transmembrane Protein 20%
• Membrane Protein 20%