Lipophagy-derived fatty acids undergo extracellular efflux via lysosomal exocytosis

Keyphrases

• Acid Inhibition 8%
• Actin Gene 8%
• Adjacent Cell 8%
• ADRA1A 8%
• Adrenergic Receptors 8%
• Albumin 8%
• ATG5 16%
• ATG7 8%
• Autophagic Degradation 8%
• Autophagosome-lysosome Fusion 16%
• Autophagy 16%
• Autophagy Pathway 8%
• Autophagy Regulators 8%
• Bafilomycin A1 8%
• Beclin-1 8%
• BECN1 8%
• Bovine Serum Albumin 8%
• Catalytic Subunit 8%
• Cathepsin B 8%
• CDH1 8%
• Cell-to-cell 8%
• Cellular Lipids 8%
• Channel Protein 8%
• Chloroquine 8%
• Diacylglycerol O-acyltransferase 8%
• Directed Transport 8%
• E-cadherin 8%
• Efflux 100%
• Extracellular Fatty Acid 8%
• Fatty Acids 100%
• High-fat Diet 8%
• LAMP1 8%
• LAMP2 8%
• Lipase A 8%
• Lipid Degradation 8%
• Lipid Droplets 25%
• Lipid Exchange 8%
• Lipid Signaling 8%
• Lipid Turnover 8%
• Lipophagy 100%
• Low-density Lipoprotein 8%
• Lysosomal Acid Lipase 8%
• Lysosomal Ca2+ 8%
• Lysosomal Exocytosis 100%
• Lysosomal Lipids 8%
• Lysosomal Membrane 8%
• MAP1LC3B 8%
• MCOLN1 25%
• Membrane Fusion 8%
• Methyl Ester 8%
• Microtubule-associated Protein 1 Light Chain 3 8%
• Mouse Embryonic Fibroblasts 8%
• Mucolipin 16%
• Nutrient Deprivation 16%
• Overexpression 16%
• PBS Phosphate Buffered Saline 8%
• Perilipin 8%
• Phosphoinositide 3-kinase (PI3K) 8%
• PIK3C3 8%
• Plasma Membrane 25%
• PNPLA2 25%
• PNPLA3 16%
• Re-esterification 8%
• Reuptake 8%
• RUBCN 8%
• Rubicon 8%
• Sequestration 8%
• SM Sphingomyelin 8%
• Transmembrane Protein 8%
• Triacylglycerol 8%
• TRPML1 16%
• Vps34 8%
• β-hydroxybutyrate 8%

Biochemistry, Genetics and Molecular Biology

• Albumin 12%
• Alpha-1A Adrenergic Receptor 12%
• ATG5 12%
• ATG7 12%
• Autophagy 75%
• Bafilomycin 12%
• BECN1 12%
• Beta-Actin 12%
• Bovine Serum Albumin 37%
• Cadherin 12%
• Calcium Channel 12%
• Cathepsin B 12%
• Cell Membrane 37%
• Channel Protein 12%
• Diglyceride 12%
• Drive 12%
• Enzyme Active Site 12%
• Esterification 12%
• Exocytosis 100%
• Fibroblast 12%
• LAMP1 12%
• Light Chain 12%
• Lipid 12%
• Lipid Degradation 12%
• Lipid Droplet 37%
• Lipid Metabolism 12%
• Lipophagocytosis 100%
• MCOLN1 37%
• Membrane Protein 12%
• Microtubule-Associated Protein 12%
• N-Acetyltransferase 12%
• Pancreatic Lipase 12%
• Patatin-Like Phospholipase 25%
• Perilipin 12%
• Phosphate Buffered Saline 12%
• Phosphoinositide 3-Kinase 12%
• Reuptake 12%
• Sphingomyelin 12%
• Synapsin I 25%
• Transmembrane Protein 25%
• Triacylglycerol Lipase 12%
• Triglyceride 12%
• Very Low-Density Lipoprotein 12%