The relationships between the solute capacity factor and Relchardt's E τ or the Kamlet-Taft π* scale in hydroorganic mixtures have been studied for a series of alkylbenzenes. It has been shown that, for such simple nonpolar solutes, linearity in plots of in k' against a single solvent polarity parameter is observed only over a limited range in composition. At least two solvent parameters are needed In order to account for the cavity formation and solute-solvent Interaction processes that control retention in reversed-phase liquid chromatography.
|Original language||English (US)|
|Number of pages||6|
|State||Published - Jul 1989|