TY - JOUR
T1 - Limitations in the Assessment of DSM-IV Cannabis Tolerance as an Indicator of Dependence in Adolescents
AU - Chung, Tammy
AU - Martin, Christopher S.
AU - Cornelius, Jack R.
AU - Winters, Ken C.
AU - Langenbucher, James W.
PY - 2004/5
Y1 - 2004/5
N2 - The usefulness of the Diagnostic and Statistical Manual's (4th ed.; DSM-IV; American Psychiatric Association, 1994) tolerance criterion as an indicator of dependence has been debated. The authors of this study evaluated the performance of DSM's cannabis tolerance criterion, operationally defined as a percentage increase in quantity needed to get high, in distinguishing adolescents with and without cannabis dependence. Two samples of adolescent cannabis users (ages 12-19) provided data (ns = 417 and 380). Tolerance, defined as a percentage increase (median increase = 300% and 175%, respectively, in the samples), had only moderate overall sensitivity and specificity in distinguishing those with and without cannabis dependence. Results suggest limitations of the DSM-IV's change-based operational definition of tolerance in adolescents.
AB - The usefulness of the Diagnostic and Statistical Manual's (4th ed.; DSM-IV; American Psychiatric Association, 1994) tolerance criterion as an indicator of dependence has been debated. The authors of this study evaluated the performance of DSM's cannabis tolerance criterion, operationally defined as a percentage increase in quantity needed to get high, in distinguishing adolescents with and without cannabis dependence. Two samples of adolescent cannabis users (ages 12-19) provided data (ns = 417 and 380). Tolerance, defined as a percentage increase (median increase = 300% and 175%, respectively, in the samples), had only moderate overall sensitivity and specificity in distinguishing those with and without cannabis dependence. Results suggest limitations of the DSM-IV's change-based operational definition of tolerance in adolescents.
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U2 - 10.1037/1064-1297.12.2.136
DO - 10.1037/1064-1297.12.2.136
M3 - Article
C2 - 15122958
AN - SCOPUS:2342444668
SN - 1064-1297
VL - 12
SP - 136
EP - 146
JO - Experimental and Clinical Psychopharmacology
JF - Experimental and Clinical Psychopharmacology
IS - 2
ER -
