LIM homeobox transcription factor Lhx2 inhibits skeletal muscle differentiation in part via transcriptional activation of Msx1 and Msx2

Biochemistry, Genetics and Molecular Biology

• Myogenesis 100%
• Homeobox 100%
• Transactivation 100%
• Skeletal Muscle 100%
• Transcription Initiation 100%
• Transcription Factors 100%
• Genomics 66%
• Messenger RNA 66%
• Small Interfering RNA 33%
• Electrophoretic Mobility Shift Assay 33%
• Chromatin Immunoprecipitation 33%
• Stem Cell 33%
• Homeostasis 33%
• Multigene Family 33%
• Enhancer Region 33%
• Binding Site 33%
• Limb Bud 33%
• C2C12 33%
• Transforming Growth Factor Beta 33%
• Luciferase 33%
• Bone Morphogenetic Protein 4 33%
• Cell Dedifferentiation 33%
• Hematopoietic Cell 33%

Keyphrases

• Transcriptional Activation 100%
• Homeobox Genes 100%
• MSX1 100%
• Lhx2 100%
• Skeletal muscle Differentiation 100%
• MSX2 100%
• LIM-homeobox 100%
• Overexpression 25%
• MRNA Level 16%
• Genomic Regions 16%
• Skeletal muscle Development 16%
• Small Interfering RNA (siRNA) 8%
• Self-renewal 8%
• Homeostasis 8%
• Mouse Embryo 8%
• Transforming Growth Factor-β 8%
• Hematopoietic Stem Cells 8%
• Chromatin 8%
• Neuronal Development 8%
• Knockdown 8%
• Hair Follicle Stem Cells 8%
• Electrophoretic Mobility Shift Assay 8%
• Inhibitory Factors 8%
• Chromatin Immunoprecipitation (ChIP) 8%
• Myotubes 8%
• DNA Complex 8%
• Complexity Bounds 8%
• Bone Morphogenetic Protein 4 (BMP4) 8%
• Downstream Target Genes 8%
• Limb Bud 8%
• Transcriptional Targets 8%
• Luciferase Reporter Assay 8%
• Dedifferentiation 8%
• C2C12 Cells 8%
• Consensus Binding Site 8%
• Family Gene 8%
• Enhancer Region 8%
• Forming Capacity 8%
• Stem Cell Renewal 8%
• Beta Family 8%
• Multiple Differentiation 8%
• RNA-based 8%
• Primary Myoblasts 8%