Ligand-Selective Wnt Receptor Complexes in CNS Blood Vessels: RECK and GPR124 Plugged In

Harald J. Junge

doi:10.1016/j.neuron.2017.08.026

Ligand-Selective Wnt Receptor Complexes in CNS Blood Vessels: RECK and GPR124 Plugged In

Harald J. Junge

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

CNS angiogenesis and blood-brain barrier integrity are controlled by the canonical Wnt pathway. In this issue of Neuron, Cho et al. (2017) use advanced mouse genetics and biochemical experiments to unravel the ligand-specific association of membrane proteins GPR124 and RECK with Wnt receptor complexes.

Original language	English (US)
Pages (from-to)	983-985
Number of pages	3
Journal	Neuron
Volume	95
Issue number	5
DOIs	https://doi.org/10.1016/j.neuron.2017.08.026
State	Published - Aug 30 2017
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2017 Elsevier Inc.

Keywords

Gpr124
Reck
Wnt7
angiogenesis
blood-brain barrier
co-activator
ligand specificity
receptor complex

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.neuron.2017.08.026

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title = "Ligand-Selective Wnt Receptor Complexes in CNS Blood Vessels: RECK and GPR124 Plugged In",

abstract = "CNS angiogenesis and blood-brain barrier integrity are controlled by the canonical Wnt pathway. In this issue of Neuron, Cho et al. (2017) use advanced mouse genetics and biochemical experiments to unravel the ligand-specific association of membrane proteins GPR124 and RECK with Wnt receptor complexes.",

keywords = "Gpr124, Reck, Wnt7, angiogenesis, blood-brain barrier, co-activator, ligand specificity, receptor complex",

author = "Junge, \{Harald J.\}",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

year = "2017",

month = aug,

day = "30",

doi = "10.1016/j.neuron.2017.08.026",

language = "English (US)",

volume = "95",

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TY - JOUR

T1 - Ligand-Selective Wnt Receptor Complexes in CNS Blood Vessels

T2 - RECK and GPR124 Plugged In

AU - Junge, Harald J.

PY - 2017/8/30

Y1 - 2017/8/30

N2 - CNS angiogenesis and blood-brain barrier integrity are controlled by the canonical Wnt pathway. In this issue of Neuron, Cho et al. (2017) use advanced mouse genetics and biochemical experiments to unravel the ligand-specific association of membrane proteins GPR124 and RECK with Wnt receptor complexes.

AB - CNS angiogenesis and blood-brain barrier integrity are controlled by the canonical Wnt pathway. In this issue of Neuron, Cho et al. (2017) use advanced mouse genetics and biochemical experiments to unravel the ligand-specific association of membrane proteins GPR124 and RECK with Wnt receptor complexes.

KW - Gpr124

KW - Reck

KW - Wnt7

KW - angiogenesis

KW - blood-brain barrier

KW - co-activator

KW - ligand specificity

KW - receptor complex

UR - https://www.scopus.com/pages/publications/85028571680

UR - https://www.scopus.com/inward/citedby.url?scp=85028571680&partnerID=8YFLogxK

U2 - 10.1016/j.neuron.2017.08.026

DO - 10.1016/j.neuron.2017.08.026

M3 - Short survey

C2 - 28858624

AN - SCOPUS:85028571680

SN - 0896-6273

VL - 95

SP - 983

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JO - Neuron

JF - Neuron

IS - 5

ER -

Ligand-Selective Wnt Receptor Complexes in CNS Blood Vessels: RECK and GPR124 Plugged In

Abstract

Bibliographical note

Keywords

UN SDGs

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