Levels of immunoreactive dynorphin in brain and pituitary of hyperthyroid and hypothyroid rats

John E. Morley, Michael K. Elson, Allen S Levine, Rex B. Shafer

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Dynorphin is a potent opioid peptide. Using a highly sensitive radioimmunoassay we have measured the levels of immunoreactive (ir) dynorphin in the cortex, hypothalamus, anterior and posterior pituitary in hyperthyroid and hypothyroid rats. Ir dynorphin levels were increased in the cortex of hypothyroid animals and decreased in the hypothalamus of hyperthyroid rats.

Original languageEnglish (US)
Pages (from-to)125-127
Number of pages3
JournalEuropean Journal of Pharmacology
Volume78
Issue number1
DOIs
StatePublished - Feb 19 1982

Fingerprint

Dynorphins
Hyperthyroidism
Brain
Posterior Hypothalamus
Anterior Hypothalamus
Opioid Peptides
Hypothalamus
Radioimmunoassay

Keywords

  • Dynorphin
  • Hyperthyroidism
  • Hypothalamus
  • Hypothyroidism
  • Pituitary

Cite this

Levels of immunoreactive dynorphin in brain and pituitary of hyperthyroid and hypothyroid rats. / Morley, John E.; Elson, Michael K.; Levine, Allen S; Shafer, Rex B.

In: European Journal of Pharmacology, Vol. 78, No. 1, 19.02.1982, p. 125-127.

Research output: Contribution to journalArticle

Morley, John E. ; Elson, Michael K. ; Levine, Allen S ; Shafer, Rex B. / Levels of immunoreactive dynorphin in brain and pituitary of hyperthyroid and hypothyroid rats. In: European Journal of Pharmacology. 1982 ; Vol. 78, No. 1. pp. 125-127.
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