Leukodystrophy: Basic and clinical

Gerald V. Raymond

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations


Leukodystrophies are serious, progressive, genetic disorders of CNS myelin. They may result from abnormalities of the oligodendrocyte or any of the other of myriad of supporting cells or tissues. With recent developments in neuroimaging, their presence is becoming increasingly noted even in situations where they were not suspected. More importantly, new genetic tools have improved our ability to diagnose. An understanding of pathogenesis is still evolving, but it is expected that this will assist in developing targeted therapies for these devastating disorders.

Original languageEnglish (US)
Title of host publicationAdvances in Neurobiology
PublisherSpringer New York LLC
Number of pages18
StatePublished - Jan 1 2017

Publication series

NameAdvances in Neurobiology
ISSN (Print)2190-5215


  • Adrenoleukodystrophy
  • Alexander disease
  • Globoid cell leukodystrophy
  • Leukodystrophy
  • Myelin


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