Left intraventricular balloon pump optimization during intractable cardiac arrest

S. F. Stamatelopoulos, L. Kochilas, N. S. Saridakis, N. A. Zakopoulos, S. D. Moulopoulos

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

This work aims to determine optimal balloon shape and volume during left intraventricular balloon pumping (IABP) in the fibrillating dog heart. A balloon volume equal to the left ventricular end-diastolic volume (LVEDV) maintained a higher systolic aortic pressure and flow (106.4 ± 2.7 mmHg and 84.7 ± 2.35 ml/kg/min, x ± SEM, respectively) than a 25% smaller (97.8 ± 3.3 mmHg, P = 0.002 and 63.7 ± 4.1 ml/Kg/min, P = 0.002, respectively) or a 25% larger balloon (87.4 ± 2.3 mmHg, P = 0.002 and 70.9 ± 3.4 ml/kg/min, P = 0.002, respectively). Among 5 different balloon shapes tested, a pear-shaped balloon inflated from the apex to the base of the left ventricle induced the highest (P varying from 0.042 to 0.01, compared to the remaining balloon shapes) systolic aortic pressure and flow (104.6 ± 4.5 mmHg and 77.9 ± 1.7 mg/kg/min, respectively). In conclusion, a pear shaped balloon, inflated to a volume equal to the LVEDV, from the apex to the base of the left ventricle, induced an optimal hemodynamic effect during LVBP.

Original languageEnglish (US)
Pages (from-to)422-430
Number of pages9
JournalInternational Journal of Artificial Organs
Volume19
Issue number7
DOIs
StatePublished - 1996
Externally publishedYes

Keywords

  • Assistance for intractable cardiac arrest
  • Intractable cardiac arrest
  • Intraventricular balloon pumping optimization

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