Latent inhibition in low and high "psychotic-prone" normal subjects

R. E. Lubow, Y. Ingberg-Sachs, N. Zalstein-Orda, J. C. Gewirtz

Research output: Contribution to journalArticlepeer-review

141 Scopus citations


Two experiments were performed with adult human subjects which demonstrated latent inhibition, a retardation of learning following preexposure to a subsequently relevant stimulus. The first study, using an auditory procedure, replicated Baruch. Hemsley and Gray's (1988a, Personality and Individual Differences, 9; finding that high "psychotic-prone" normals, as assessed by Eysenck's Psychoticism Scale and Claridge and Brok's STA Scale, exhibit an attenuated latent inhibition effect as compared to low "psychotic-prones". The second study, using a newly developed visual procedure, obtained similar results. The attenuation of latent inhibition in high "psychotic-prone" normals was discussed in relation to attentional dysfunction in schizophrenia and the animal dopamine model of schizophrenia.

Original languageEnglish (US)
Pages (from-to)563-572
Number of pages10
JournalPersonality and Individual Differences
Issue number5
StatePublished - May 1992


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