Late-stage [18F]fluorination: New solutions to old problems

Allen F. Brooks; Joseph J. Topczewski; Naoko Ichiishi; Melanie S. Sanford; Peter J.H. Scott

doi:10.1039/c4sc02099e

Late-stage [¹⁸F]fluorination: New solutions to old problems

Allen F. Brooks, Joseph J. Topczewski, Naoko Ichiishi, Melanie S. Sanford, Peter J.H. Scott

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

258 Scopus citations

Abstract

The last 2–3 years have seen numerous relationships develop between organometallic chemists, fluorine chemists and PET Centers around the world. These collaborations have led to the development of many new strategies for the late-stage introduction of fluorine-18 into complex bioactive molecules. In this perspective we highlight recent developments and key milestones since 2011.

Original language	English (US)
Pages (from-to)	4545-4553
Number of pages	9
Journal	Chemical Science
Volume	5
Issue number	12
DOIs	https://doi.org/10.1039/c4sc02099e
State	Published - Oct 28 2014

Publisher link

10.1039/c4sc02099e

Find It

Find It at U of M Libraries

Cite this

@article{dcf0b1b4f19049cd9fac13ea1e0fb479,

title = "Late-stage [18F]fluorination: New solutions to old problems",

abstract = "The last 2–3 years have seen numerous relationships develop between organometallic chemists, fluorine chemists and PET Centers around the world. These collaborations have led to the development of many new strategies for the late-stage introduction of fluorine-18 into complex bioactive molecules. In this perspective we highlight recent developments and key milestones since 2011.",

author = "Brooks, {Allen F.} and Topczewski, {Joseph J.} and Naoko Ichiishi and Sanford, {Melanie S.} and Scott, {Peter J.H.}",

year = "2014",

month = oct,

day = "28",

doi = "10.1039/c4sc02099e",

language = "English (US)",

volume = "5",

pages = "4545--4553",

journal = "Chemical Science",

issn = "2041-6520",

publisher = "Royal Society of Chemistry",

number = "12",

}

TY - JOUR

T1 - Late-stage [18F]fluorination

T2 - New solutions to old problems

AU - Brooks, Allen F.

AU - Topczewski, Joseph J.

AU - Ichiishi, Naoko

AU - Sanford, Melanie S.

AU - Scott, Peter J.H.

PY - 2014/10/28

Y1 - 2014/10/28

N2 - The last 2–3 years have seen numerous relationships develop between organometallic chemists, fluorine chemists and PET Centers around the world. These collaborations have led to the development of many new strategies for the late-stage introduction of fluorine-18 into complex bioactive molecules. In this perspective we highlight recent developments and key milestones since 2011.

AB - The last 2–3 years have seen numerous relationships develop between organometallic chemists, fluorine chemists and PET Centers around the world. These collaborations have led to the development of many new strategies for the late-stage introduction of fluorine-18 into complex bioactive molecules. In this perspective we highlight recent developments and key milestones since 2011.

UR - http://www.scopus.com/inward/record.url?scp=84908413232&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908413232&partnerID=8YFLogxK

U2 - 10.1039/c4sc02099e

DO - 10.1039/c4sc02099e

M3 - Article

AN - SCOPUS:84908413232

SN - 2041-6520

VL - 5

SP - 4545

EP - 4553

JO - Chemical Science

JF - Chemical Science

IS - 12

ER -

Late-stage [¹⁸F]fluorination: New solutions to old problems

Abstract

Publisher link

Find It

Other files and links

Fingerprint

Cite this