Late-stage [18F]fluorination: New solutions to old problems

Allen F. Brooks, Joseph J. Topczewski, Naoko Ichiishi, Melanie S. Sanford, Peter J.H. Scott

Research output: Contribution to journalArticlepeer-review

249 Scopus citations


The last 2–3 years have seen numerous relationships develop between organometallic chemists, fluorine chemists and PET Centers around the world. These collaborations have led to the development of many new strategies for the late-stage introduction of fluorine-18 into complex bioactive molecules. In this perspective we highlight recent developments and key milestones since 2011.

Original languageEnglish (US)
Pages (from-to)4545-4553
Number of pages9
JournalChemical Science
Issue number12
StatePublished - Oct 28 2014


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