Late airflow obstruction in heart-lung transplantation recipients

C. M. Burke, A. J.R. Morris, K. D. Dawkins, C. G. McGregor, S. A. Yousem, M. Allen, J. Theodore, J. Harvey, M. E. Billingham, P. E. Oyer

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22 Scopus citations


Five of seventeen long-term survivors of heart-lung transplanatation developed a progressive obstructive ventilatory defect which was refractory to treatment. Since then, two other recipients developed airflow obstruction which, in one, was completely reversed by early treatment with augmented corticosteroids. Physiological markers of disease in the transplanted lung were identified. Such markers may be useful in the management of heart-lung recipients by detecting, at an early stage, post-transplant pulmonary disease when the pathological process may still be reversible by augmented corticosteroid treatment.

Original languageEnglish (US)
Pages (from-to)437-440
Number of pages4
JournalJournal of Heart Transplantation
Issue number4
StatePublished - 1984
Externally publishedYes


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