Laparoscopic resection of an undifferentiated pleomorphic splenic sarcoma

Asra Hashmi, Eitan Podgaetz, Melanie L. Richards

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Background: Splenic tumors are rare. Malignant fibrous histiocytoma (MFH) of the spleen is one of the least common primary splenic tumors. Review of the literature shows that a laparoscopic resection has never been tried. Method: We discuss the case of a 76-year-old man with a 7-cm MFH in the spleen and present a review of splenic sarcomas. Results: The patient underwent a successful laparoscopic splenectomy; pathology revealed a rare undifferentiated pleomorphic sarcoma of the spleen. A review of the international literature identified 15 additional cases of primary splenic MFH. Survival was rarely longer than 15 months. Conclusion: Malignant fibrous histiocytoma of the spleen is an exceedingly rare tumor with a poor prognosis. In experienced hands, laparoscopic splenectomy is a feasible operative choice for primary splenic sarcoma.

Original languageEnglish (US)
Pages (from-to)426-430
Number of pages5
JournalJournal of the Society of Laparoendoscopic Surgeons
Issue number3
StatePublished - Jul 2010
Externally publishedYes


  • Laparoscopic splenectomy
  • Malignant fibrous histiocytoma
  • Undifferentiated pleomorphic sarcoma


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