TY - JOUR
T1 - Lack of usefulness of electron beam computed tomography for detecting coronary allograft vasculopathy
AU - Ratliff, Norman B.
AU - Jorgensen, Charles R.
AU - Gobel, Fredarick L.
AU - Hodges, Morrison
AU - Knickelbine, Thomas
AU - Pritzker, Mark R.
N1 - Funding Information:
This study was supported by the Minneapolis Heart Institute Foundation, Minneapolis, Minnesota.
Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2004/7/15
Y1 - 2004/7/15
N2 - Fifty-five patients with cardiac allografts were studied by electron beam computed tomography for coronary calcification (EBCT CC) and coronary arteriography, and from the latter, a coronary index was calculated using the size, degree of obstruction, and linear extent of disease of each vessel. There was a significant correlation between EBCT CC score and coronary index, but receiver-operating characteristic (ROC) analysis demonstrated unsatisfactory performance of EBCT CC, and 6 patients had no coronary calcification despite having very abnormal coronary indexes. There are pathologic differences between coronary allograft vasculopathy and atherosclerosis, and correspondingly, EBCT CC has limited usefulness in the cardiac transplant population.
AB - Fifty-five patients with cardiac allografts were studied by electron beam computed tomography for coronary calcification (EBCT CC) and coronary arteriography, and from the latter, a coronary index was calculated using the size, degree of obstruction, and linear extent of disease of each vessel. There was a significant correlation between EBCT CC score and coronary index, but receiver-operating characteristic (ROC) analysis demonstrated unsatisfactory performance of EBCT CC, and 6 patients had no coronary calcification despite having very abnormal coronary indexes. There are pathologic differences between coronary allograft vasculopathy and atherosclerosis, and correspondingly, EBCT CC has limited usefulness in the cardiac transplant population.
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U2 - 10.1016/j.amjcard.2004.03.064
DO - 10.1016/j.amjcard.2004.03.064
M3 - Article
C2 - 15246902
AN - SCOPUS:3142604934
SN - 0002-9149
VL - 94
SP - 202
EP - 206
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 2
ER -
