Lack of usefulness of electron beam computed tomography for detecting coronary allograft vasculopathy

Norman B. Ratliff; Charles R. Jorgensen; Fredarick L. Gobel; Morrison Hodges; Thomas Knickelbine; Mark R. Pritzker

doi:10.1016/j.amjcard.2004.03.064

Lack of usefulness of electron beam computed tomography for detecting coronary allograft vasculopathy

Norman B. Ratliff, Charles R. Jorgensen, Fredarick L. Gobel, Morrison Hodges, Thomas Knickelbine, Mark R. Pritzker

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Fifty-five patients with cardiac allografts were studied by electron beam computed tomography for coronary calcification (EBCT CC) and coronary arteriography, and from the latter, a coronary index was calculated using the size, degree of obstruction, and linear extent of disease of each vessel. There was a significant correlation between EBCT CC score and coronary index, but receiver-operating characteristic (ROC) analysis demonstrated unsatisfactory performance of EBCT CC, and 6 patients had no coronary calcification despite having very abnormal coronary indexes. There are pathologic differences between coronary allograft vasculopathy and atherosclerosis, and correspondingly, EBCT CC has limited usefulness in the cardiac transplant population.

Original language	English (US)
Pages (from-to)	202-206
Number of pages	5
Journal	American Journal of Cardiology
Volume	94
Issue number	2
DOIs	https://doi.org/10.1016/j.amjcard.2004.03.064
State	Published - Jul 15 2004
Externally published	Yes

Bibliographical note

Funding Information:
This study was supported by the Minneapolis Heart Institute Foundation, Minneapolis, Minnesota.

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

Publisher link

10.1016/j.amjcard.2004.03.064

Find It

Find It at U of M Libraries

Cite this

@article{54c2d839522c4984b3641182735e72aa,

title = "Lack of usefulness of electron beam computed tomography for detecting coronary allograft vasculopathy",

abstract = "Fifty-five patients with cardiac allografts were studied by electron beam computed tomography for coronary calcification (EBCT CC) and coronary arteriography, and from the latter, a coronary index was calculated using the size, degree of obstruction, and linear extent of disease of each vessel. There was a significant correlation between EBCT CC score and coronary index, but receiver-operating characteristic (ROC) analysis demonstrated unsatisfactory performance of EBCT CC, and 6 patients had no coronary calcification despite having very abnormal coronary indexes. There are pathologic differences between coronary allograft vasculopathy and atherosclerosis, and correspondingly, EBCT CC has limited usefulness in the cardiac transplant population.",

author = "Ratliff, {Norman B.} and Jorgensen, {Charles R.} and Gobel, {Fredarick L.} and Morrison Hodges and Thomas Knickelbine and Pritzker, {Mark R.}",

year = "2004",

month = jul,

day = "15",

doi = "10.1016/j.amjcard.2004.03.064",

language = "English (US)",

volume = "94",

pages = "202--206",

journal = "American Journal of Cardiology",

issn = "0002-9149",

publisher = "Elsevier Inc.",

number = "2",

}

TY - JOUR

T1 - Lack of usefulness of electron beam computed tomography for detecting coronary allograft vasculopathy

AU - Ratliff, Norman B.

AU - Jorgensen, Charles R.

AU - Gobel, Fredarick L.

AU - Hodges, Morrison

AU - Knickelbine, Thomas

AU - Pritzker, Mark R.

PY - 2004/7/15

Y1 - 2004/7/15

N2 - Fifty-five patients with cardiac allografts were studied by electron beam computed tomography for coronary calcification (EBCT CC) and coronary arteriography, and from the latter, a coronary index was calculated using the size, degree of obstruction, and linear extent of disease of each vessel. There was a significant correlation between EBCT CC score and coronary index, but receiver-operating characteristic (ROC) analysis demonstrated unsatisfactory performance of EBCT CC, and 6 patients had no coronary calcification despite having very abnormal coronary indexes. There are pathologic differences between coronary allograft vasculopathy and atherosclerosis, and correspondingly, EBCT CC has limited usefulness in the cardiac transplant population.

AB - Fifty-five patients with cardiac allografts were studied by electron beam computed tomography for coronary calcification (EBCT CC) and coronary arteriography, and from the latter, a coronary index was calculated using the size, degree of obstruction, and linear extent of disease of each vessel. There was a significant correlation between EBCT CC score and coronary index, but receiver-operating characteristic (ROC) analysis demonstrated unsatisfactory performance of EBCT CC, and 6 patients had no coronary calcification despite having very abnormal coronary indexes. There are pathologic differences between coronary allograft vasculopathy and atherosclerosis, and correspondingly, EBCT CC has limited usefulness in the cardiac transplant population.

UR - http://www.scopus.com/inward/record.url?scp=3142604934&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3142604934&partnerID=8YFLogxK

U2 - 10.1016/j.amjcard.2004.03.064

DO - 10.1016/j.amjcard.2004.03.064

M3 - Article

C2 - 15246902

AN - SCOPUS:3142604934

VL - 94

SP - 202

EP - 206

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 2

ER -

Lack of usefulness of electron beam computed tomography for detecting coronary allograft vasculopathy

Abstract

Bibliographical note

Publisher link

Find It

Other files and links

Fingerprint

Cite this