Lack of consensus in the diagnosis and treatment for ocular tuberculosis among uveitis specialists

Susan M. Lou, Kelly L. Larkin, Kevin Winthrop, James T. Rosenbaum, Massimo Accorinti, Sofia Androudi, Lourdes Arellanes, Matthias Becker, Bahram Bodaghi, Soon Phaik Chee, Smet De Smet, D. Marc, Michal Kramer, Genevieve Larkin, Sue Lightman, Lyndell Lim, Juan Lopez, Friederike Mackensen, Peter McCluskey, Cristina MuccioliA. Okada Annabelle, Narciss Okhravi, Daniel Vasconcelos-Santos, Peter Mc Cluskey Zamir, Manfred Zierhut, Nisha Acharya, Andrea Birnbaum, Nicholas J. Butler, David Callanan, Emmett Cunningham, Sam Dahr, Janet L. Davis, Larissa Derzko-Dzulynsky, James Dunn, Albert O. Edwards, Lisa Faia, Naomi Falk, Farzin Forooghian, C. Stephen Foster, Alan H. Friedman, Sunir Garg, Paul Gaudio, Ronald Gentile, Debra Goldstein, Douglas Jabs, Glen Jaffe, Kashyap Kansupada, Henry Kaplan, Sanjay Kedhar, Robert Beardsley, Uveitis Specialists Study Group

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Purpose: To assess the approach of specialists to ocular tuberculosis (TB). Methods: The American Uveitis Society (AUS) Listserv was surveyed using two clinical cases and general questions. Results: Of 196 members, 87 responded (44.4%), of whom 64 were affiliated with practices in North America, while 23 were outside of North America. The survey provided normative data on how physicians evaluate patients with uveitis as well as opinions about ocular TB. Responses varied widely on such issues as (1) the pretest probability that a patient with granulomatous panuveitis had TB uveitis (range 1-75%) or that a patient with a risk factor for TB had ocular TB (range 0-90%); (2) the optimal duration of anti-TB therapy; and (3) whether therapy should be discontinued after 2 months in nonresponders. Conclusions: Consensus is lacking among uveitis specialists for the diagnosis or management of ocular TB.

Original languageEnglish (US)
Pages (from-to)25-31
Number of pages7
JournalOcular Immunology and Inflammation
Volume23
Issue number1
DOIs
StatePublished - Feb 1 2015

Bibliographical note

Funding Information:
See financial disclosures in Conflict of Interest form for Dr. James T. Rosenbaum This research was supported by Research to Prevent Blindness, National Eye Institute core facility grant P30EY010572, the William and Mary Bauman Foundation, and the Stan and Madelle Rosenfeld Family Trust. The Oregon Clinical and Translational Research Institute (OCTRI) also supported this publication: grant number (UL1TR000128) from the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Publisher Copyright:
© Informa Healthcare USA, Inc.

Keywords

  • Post-test probability
  • Pretest probability
  • Tuberculosis
  • Uveitis

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