Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis

A. K. Roche; Ioannis G. Koutlas; K. C. Kajander

doi:10.1016/S0006-8993(97)01556-4

Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis

A. K. Roche, Ioannis G. Koutlas, K. C. Kajander

Oral and Maxillofacial Pathology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) and substance P-like immunoreactivity (SP-LI) were evaluated in subnucleus caudalis following induction of sinusitis. Three days after induction, intensity of labeling for CGRP-LI and SP-LI increased in ipsilateral subnucleus caudalis. Labeling for CGRP-LI and SP-LI appeared normal at later time points (20 and 28 days). Early changes in these neuropeptides may contribute to the inflammatory process and painful symptoms accompanying sinusitis.

Original language	English (US)
Pages (from-to)	283-289
Number of pages	7
Journal	Brain Research
Volume	791
Issue number	1-2
DOIs	https://doi.org/10.1016/S0006-8993(97)01556-4
State	Published - Apr 27 1998

Bibliographical note

Funding Information:
We thank Dr. Robert Vickers for help with histopathology, and Jeffrey Zey and Angel Honda for excellent technical assistance. We also thank Dr. Jean Xu for help with evaluating the sections. We are grateful to Drs. Glenn Giesler and Don Simone for careful comments on an earlier version of this manuscript. This research was supported by grants from the National Institute for Dental Research (DE 10227) and from the National Institute for Neurological Diseases and Strokes (NS 29567 and NS 33908).

Keywords

Inflammation
Neuropeptide
Spinal
Trigeminal nucleus
Trigeminal nucleus

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@article{40fcb82002eb4a8eb4673501f28bab97,

title = "Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis",

abstract = "Calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) and substance P-like immunoreactivity (SP-LI) were evaluated in subnucleus caudalis following induction of sinusitis. Three days after induction, intensity of labeling for CGRP-LI and SP-LI increased in ipsilateral subnucleus caudalis. Labeling for CGRP-LI and SP-LI appeared normal at later time points (20 and 28 days). Early changes in these neuropeptides may contribute to the inflammatory process and painful symptoms accompanying sinusitis.",

keywords = "Inflammation, Neuropeptide, Spinal, Trigeminal nucleus, Trigeminal nucleus",

author = "Roche, {A. K.} and Koutlas, {Ioannis G.} and Kajander, {K. C.}",

note = "Funding Information: We thank Dr. Robert Vickers for help with histopathology, and Jeffrey Zey and Angel Honda for excellent technical assistance. We also thank Dr. Jean Xu for help with evaluating the sections. We are grateful to Drs. Glenn Giesler and Don Simone for careful comments on an earlier version of this manuscript. This research was supported by grants from the National Institute for Dental Research (DE 10227) and from the National Institute for Neurological Diseases and Strokes (NS 29567 and NS 33908).",

year = "1998",

month = apr,

day = "27",

doi = "10.1016/S0006-8993(97)01556-4",

language = "English (US)",

volume = "791",

pages = "283--289",

journal = "Brain Research",

issn = "0006-8993",

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TY - JOUR

T1 - Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis

AU - Roche, A. K.

AU - Koutlas, Ioannis G.

AU - Kajander, K. C.

N1 - Funding Information: We thank Dr. Robert Vickers for help with histopathology, and Jeffrey Zey and Angel Honda for excellent technical assistance. We also thank Dr. Jean Xu for help with evaluating the sections. We are grateful to Drs. Glenn Giesler and Don Simone for careful comments on an earlier version of this manuscript. This research was supported by grants from the National Institute for Dental Research (DE 10227) and from the National Institute for Neurological Diseases and Strokes (NS 29567 and NS 33908).

PY - 1998/4/27

Y1 - 1998/4/27

N2 - Calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) and substance P-like immunoreactivity (SP-LI) were evaluated in subnucleus caudalis following induction of sinusitis. Three days after induction, intensity of labeling for CGRP-LI and SP-LI increased in ipsilateral subnucleus caudalis. Labeling for CGRP-LI and SP-LI appeared normal at later time points (20 and 28 days). Early changes in these neuropeptides may contribute to the inflammatory process and painful symptoms accompanying sinusitis.

AB - Calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) and substance P-like immunoreactivity (SP-LI) were evaluated in subnucleus caudalis following induction of sinusitis. Three days after induction, intensity of labeling for CGRP-LI and SP-LI increased in ipsilateral subnucleus caudalis. Labeling for CGRP-LI and SP-LI appeared normal at later time points (20 and 28 days). Early changes in these neuropeptides may contribute to the inflammatory process and painful symptoms accompanying sinusitis.

KW - Inflammation

KW - Neuropeptide

KW - Spinal

KW - Trigeminal nucleus

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UR - http://www.scopus.com/inward/citedby.url?scp=0032571788&partnerID=8YFLogxK

U2 - 10.1016/S0006-8993(97)01556-4

DO - 10.1016/S0006-8993(97)01556-4

M3 - Article

C2 - 9593942

AN - SCOPUS:0032571788

VL - 791

SP - 283

EP - 289

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1-2

ER -

Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis

Abstract

Bibliographical note

Keywords

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