Abstract
Calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) and substance P-like immunoreactivity (SP-LI) were evaluated in subnucleus caudalis following induction of sinusitis. Three days after induction, intensity of labeling for CGRP-LI and SP-LI increased in ipsilateral subnucleus caudalis. Labeling for CGRP-LI and SP-LI appeared normal at later time points (20 and 28 days). Early changes in these neuropeptides may contribute to the inflammatory process and painful symptoms accompanying sinusitis.
Original language | English (US) |
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Pages (from-to) | 283-289 |
Number of pages | 7 |
Journal | Brain Research |
Volume | 791 |
Issue number | 1-2 |
DOIs | |
State | Published - Apr 27 1998 |
Keywords
- Inflammation
- Neuropeptide
- Spinal
- Trigeminal nucleus
- Trigeminal nucleus