Label-free biosensing platform with low-voltage electrolyte-gated transistors

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

We present a strategy to measure DNA hybridization in a manner applicable to portable sensors. An electrolyte-gated transistor (EGT) serves as a transducer for surface hybridization of DNA. The key aspect of the design is the use of a floating-gate electrode which serves as an active sensor area while also connecting the EGT to an aqueous buffer containing analyte molecules. When DNA is hybridized at the floating-gate it shifts the effective voltage used to drive current through the EGT. The sensing strategy can be readily integrated into a microfluidic system and carried over to other classes of biomarkers.

Original languageEnglish (US)
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages2047-2049
Number of pages3
ISBN (Electronic)9780979806476
StatePublished - Jan 1 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014Oct 30 2014

Publication series

Name18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period10/26/1410/30/14

Keywords

  • Biosensor
  • Label-Free
  • Organic transistor

Fingerprint Dive into the research topics of 'Label-free biosensing platform with low-voltage electrolyte-gated transistors'. Together they form a unique fingerprint.

Cite this