Kinetics of DNA Adducts and Abasic Site Formation in Tissues of Mice Treated with a Nitrogen Mustard

Keyphrases

• DNA Adducts 100%
• Site Formation 100%
• Abasic Site 100%
• Nitrogen mustard 100%
• Apurinic Sites 29%
• Liver 8%
• Nitrogen Removal 8%
• Basal Level 8%
• Removal Rate 8%
• Drug Use 4%
• DNA Sequencing 4%
• Lung 4%
• In Cancer 4%
• Quantitative Measurement 4%
• Chemotherapy 4%
• Mechanism of Action 4%
• Cancer Cells 4%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 4%
• DNA Replication 4%
• DNA Interstrand Crosslinks 4%
• Site-level 4%
• Alkylation 4%
• Guanine 4%
• DNA Damage 4%
• Spleen 4%
• Circulating Tumor DNA (ctDNA) 4%
• Tumor Development 4%
• Female Mice 4%
• Kinetic Model 4%
• Hydroxide 4%
• Ethylamine 4%
• Malignant Tumor 4%
• MDA-MB-231 4%
• Secondary Tumor 4%
• Tumor Cell Lines 4%
• Biological Processing 4%
• Depurination 4%
• Secondary Reaction 4%
• Formation Rate 4%
• Mammary Tumor Cells 4%
• Stable Ring 4%
• Formamidopyrimidines 4%
• FapyG 4%
• Chemotherapeutic Regimens 4%
• Clinical Limitations 4%

Pharmacology, Toxicology and Pharmaceutical Science

• Nitrogen Mustard 100%
• Malignant Neoplasm 8%
• Chemotherapy 4%
• Biological Marker 4%
• Antiinfective Agent 4%
• Breast Tumor 4%
• DNA Base 4%
• Neoplasm 4%
• Guanine 4%
• Ethylamine 4%