Kinetic Resolutions Using Biotransformations

Petra Gadler, Kurt Faber, Christopher K. Savile, Romas J. Kazlauskas, Andrew J. Carnell, Gary Breen

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationPractical Methods for Biocatalysis and Biotransformations
PublisherJohn Wiley & Sons, Ltd
Number of pages15
ISBN (Print)9780470519271
StatePublished - Dec 15 2009


  • Biocatalyst preparation
  • Desymmetrization of related ketones
  • Enzymatic hydrolysis of alkylsulfate esters catalysed by alkylsulfatases
  • Kinetic resolutions using biotransformations
  • Microbial hydrolysis of rac-2-octylsulfate
  • Procedure 1 - Humicola sp. Lipase BREP
  • Prochiral ketone desymmetrization using enzymes
  • Protease-catalyzed resolutions using 3-(3-Pyridine)propionyl anchor group
  • Reactions in THF using freeze-dried Amano AK PFL

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