Kinethesia is impaired in focal dystonia

Norman Putzki, Philipp Stude, Jürgen Konczak, Karoline Graf, Hans Christoph Diener, Matthias Maschke

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Parkinson's disease (PD) and focal dystonia (FD) are both predominantly characterized by motor symptoms. Also, recent research has shown that sensory processing is impaired in both movement disorders. FD is characterized by involuntary movements and abnormal limb postures; thus, abnormal kinesthesia could be involved in the pathogenesis. We examined passive index finger movements in patients with FD (n = 12) and PD (n = 11) and in age-matched healthy controls (n = 13). Compared to healthy controls, patients with PD and FD were significantly impaired in the correct detection of the movement direction. The perceptual thresholds for 75% correct responses of movement direction were 0.21 degrees for FD and 0.28 degrees for PD patients compared to 0.13 degrees in control subjects. Subjects with PD and FD were also significantly impaired when they had to judge consecutive amplitudes. Results of the present study point to impaired kinesthesia in FD. Defective sensory processing could be involved in the pathophysiology of the disease and may influence dystonic contractions.

Original languageEnglish (US)
Pages (from-to)754-760
Number of pages7
JournalMovement Disorders
Volume21
Issue number6
DOIs
StatePublished - Jun 1 2006

Keywords

  • Basal ganglia
  • Focal dystonia
  • Kinesthesia
  • Parkinson's disease
  • Proprioception

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