Killing the killer: Natural killer cells to treat Ewing's sarcoma

Research output: Contribution to journalArticle

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Abstract

Cho and coworkers show that Ewing's sarcoma cells are highly sensitive to expanded allogeneic natural killer (NK) cells, partially through a NKG2D- and DNAM-1-dependent mechanism. Using an orthotopic murine model, they also show that irradiation significantly enhances the NK-cell killing of these tumors.

Original languageEnglish (US)
Pages (from-to)3819-3821
Number of pages3
JournalClinical Cancer Research
Volume16
Issue number15
DOIs
StatePublished - Aug 1 2010

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