KDOQI US Commentary on the 2021 KDIGO Clinical Practice Guideline for the Management of Blood Pressure in CKD

Paul E. Drawz, Srinivasan Beddhu, O. N.Ray Bignall, Jordana B. Cohen, Joseph T. Flynn, Elaine Ku, Mahboob Rahman, George Thomas, Matthew R. Weir, Paul K. Whelton

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


The Kidney Disease Outcomes Quality Initiative (KDOQI) convened a work group to review the 2021 KDIGO (Kidney Disease: Improving Global Outcomes) guideline for the management of blood pressure in chronic kidney disease (CKD). This commentary is the product of that work group and presents the recommendations and practice points from the KDIGO guideline in the context of US clinical practice. A critical addition to the KDIGO guideline is the recommendation for accurate assessment of blood pressure using standardized office blood pressure measurement. In the general adult population with CKD, KDIGO recommends a goal systolic blood pressure less than 120 mm Hg on the basis of results from the Systolic Blood Pressure Intervention Trial (SPRINT) and secondary analyses of the Action to Control Cardiovascular Risk in Diabetes-Blood Pressure (ACCORD-BP) trial. The KDOQI work group agreed with most of the recommendations while highlighting the weak evidence base especially for patients with diabetes and advanced CKD.

Original languageEnglish (US)
Pages (from-to)311-327
Number of pages17
JournalAmerican Journal of Kidney Diseases
Issue number3
StatePublished - Mar 2022

Bibliographical note

Funding Information:
No financial support was required for the development of this commentary.

Publisher Copyright:
© 2021 National Kidney Foundation, Inc.


  • BP control
  • Blood pressure (BP)
  • chronic kidney disease (CKD)
  • commentary evidence-based recommendation
  • diabetes
  • dialysis
  • end-stage kidney disease (ESKD)
  • guideline implementation
  • guidelines
  • hypertension
  • nephrology best practices
  • pediatric
  • transplant

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural


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